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Table 3 Use of pain-related medications among study subjects*

From: Clinical characteristics and patterns of healthcare utilization in patients with painful neuropathic disorders in UK general practice: a retrospective cohort study

  Patients with painful neuropathies (N = 31,688) Comparison group (N = 31,688) P-Value
Number receiving    
   Antiepileptic drugs 3,838 (12.1) 283 (0.9) <0.01
   Benzodiazepines 4,127 (13.0) 1,546 (4.9) <0.01
   Corticosteroids 3,297 (10.4) 1,563 (4.9) <0.01
   Nonsteroidal anti- inflammatory drugs    
Cyclooxygenase-2 inhibitors 730 (2.3) 209 (0.7) <0.01
Other nonsteroidal anti- inflammatory drugs 17,597 (55.5) 6,946 (21.9) <0.01
Any of above 17,902 (56.5) 7,059 (22.3) <0.01
   Muscle relaxants 422 (1.3) 70 (0.2) <0.01
   Sedatives/hypnotics 1,548 (4.9) 749 (2.4) <0.01
   Opioids    
Short-acting opioids 15,587 (49.2) 4,369 (13.8) <0.01
Long-acting opioids 719 (2.3) 66 (0.2) <0.01
Any of above 15,674 (49.5) 4,388 (13.8) <0.01
   Antidepressants    
Tricyclic antidepressants 6,320 (19.9) 477 (1.5) <0.01
Monoamine oxidase inhibitors 12 (0.0) 7 (0.0) 0.25
Selective serotonin reuptake inhibitors 3,397 (10.7) 2,259 (7.1) <0.01
Other antidepressants 999 (3.2) 523 (1.7) <0.01
Any of above 9,463 (29.9) 3,038 (9.6) <0.01
   Antimigraine    
Triptans 480 (1.5) 268 (0.8) <0.01
Other antimigraine 231 (0.7) 110 (0.3) <0.01
Any of above 647 (2.0) 351 (1.1) <0.01
   Miscellaneous    
Injectable analgesics 759 (2.4) 410 (1.3) <0.01
Topical analgesics 4,258 (13.4) 2,502 (7.9) <0.01
Other 107 (0.3) 49 (0.2) <0.01
Any of above 4,941 (15.6) 2,896 (9.1) <0.01
Any of above 26,265 (82.9) 13,745 (43.4) <0.01
Number receiving    <0.01
   None of the above 5,434 (17.1) 17,952 (56.7)  
   1 of the above 7,877 (24.9) 8,047 (25.4)  
   2 of the above 7,919 (25.0) 3,677 (11.6)  
   3 of the above 5,264 (16.6) 1,368 (4.3)  
   ≥ 4 of above 5,194 (16.4) 644 (2.0)  
   Any of above 26,265 (82.9) 13,745 (43.4) <0.01
  1. *Unless otherwise indicated, all values are number (%).