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Table 1 Clinical characteristics of the study population

From: Different associations of white matter lesions with depression and cognition

 

All (n=161)

Control (n=64)

CIND (n=44)

Dementia (n=53)

p

M/F

90/71

29/35

30/14

31/22

0.06

Age, y

74.4 (7.8)

73.0 (7.0)

73.0 (7.9)

77.1 (8.1)

0.006

Education, y

14.9 (3.2)

15.5 (3.0)

15.4 (3.0)

13.7 (3.3)

0.002

MMSE

26.6 (4.3)

29.2 (1.0)

27.9 (1.7)

22.4 (5.2)

<0.001

Depressive score

1.5 (1.7)

0.5 (1.0)

1.8 (0.5)

2.4 (1.9)

<0.001

Verbal memory score

88.3 (24.0)

106.7 (15.8)

87.5 (15.3)

62.6 (15.1)

<0.001

Visual memory score

86.6 (22.4)

102.9 (12.1)

85.0 (18.3)

61.6 (14.5)

<0.001

Executive score

90.8 (18.6)

100.0 (13.8)

90.9 (17.5)

75.2 (16.7)

<0.001

Frontal gray matter volume, cm3

200.7 (13.8)

206.7 (12.7)

200.6 (12.4)

193.4 (13.0)

<0.001

White matter lesion volume, cm3

19.6 (17.7)

14.0 (6.9)

19.7 (15.6)

26.2 (23.8)

<0.001

  1. Mean (standard deviation). All gray matter volumes and WML volume were normalized to total intracranial volume. CIND, Cognitively Impaired Not Demented; MMSE, Mini-Mental State Exam.