Social and economic burden of walking and mobility problems in multiple sclerosis

BMC Neurology

Table 4 Representativeness of the PSC vs non-PSC and the T25FW and non-T25FW cohorts

Characteristic	PSC	Non-PSC	P-value	T25FW	Non-25FW	P-value
Gender, %	N = 2169	N = 1397	0.0384	N = 184	N = 3382	0.8527
Male	38	34		36	37
Female	62	66		64	63
Employment type, %	N = 1048	N = 593	0.0004	N = 98	N = 1543	0.2362
Manual skilled	25	30		22	27
Manual unskilled	15	19		12	17
Non-Manual	60	51		66	56
Time since diagnosis,
N	N = 1941	N = 1156	0.0330	N = 176	N = 2921	0.6199
Mean years	6.2	5.7		5.8	6.0
Mobility problems (PRF-reported), mean	N = 2124	N = 1381		N = 181	N = 3324
Paraesis	0.90	0.86	0.2499	0.90	0.88	0.5122
Plegia	0.25	0.26	0.9536	0.25	0.25	0.9063
Spasticity	0.59	0.48	0.0001	0.61	0.54	0.1503
Muscle atrophy	0.15	0.09	0.0001	0.03	0.14	0.0085
Spasms/cramps	0.29	0.22	0.0001	0.30	0.26	0.2680
Footdrop	0.15	0.08	0.0001	0.13	0.12	0.4241
Ataxia	0.58	0.53	0.1016	0.54	0.56	0.9508
Dystonia	0.04	0.02	0.0091	0.04	0.03	0.4537
Fatigue	0.84	0.77	0.0219	0.85	0.81	0.3428
Most recent EDSS score
N	N = 1845	N = 1211	0.5724	N = 151	N = 2905	0.4510
Mean	3.24	3.20		3.1	3.2

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