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Table 1 Meta-analysis of neurosurgical clipping vs. endovascular coiling for each outcome

From: Endovascular coiling versus neurosurgical clipping in patients with unruptured intracranial aneurysm: a systematic review

Outcome

Studies, n

Patients, n

Random effects, OR (95% CI)

Fixed effects, OR (95% CI)

I2,%*

Heterogeneity P*

Overall death

      

 Overall

5

1967

1.42 (0.50, 4.04)

1.42 (0.50, 4.04)

0

0.69

 ≤6 months measurement time

4

1950

1.25 (0.42, 3.74)

1.25 (0.42, 3.74)

0

0.65

In-hospital mortality

      

 Overall

5

 

1.55 (0.91, 2.61)

1.35 (1.07, 1.70)

52

0.08

 Adjusted OR

3

 

3.35 (0.91, 12.30)

3.46 (2.20, 5.44)

83

0.003

Disability (GOS)

      

 Overall

9

754

2.38 (1.33, 4.26)

2.38 (1.33, 4.26)

0

0.99

 ≤6 months measurement time

4

314

2.72 (1.16, 6.34)

2.72 (1.16, 6.34)

0

0.81

 >6 months measurement time

4

331

2.12 (0.93, 4.84)

2.12 (0.93, 4.84)

0

0.90

 Asian races

4

413

2.41 (1.19, 4.90)

2.41 (1.19, 4.90)

0

0.84

 Western races

5

341

2.32 (0.84, 6.39)

2.32 (0.84, 6.39)

0

0.92

Disability (mRS)

2

262

2.83 (1.42, 5.63)

2.83 (1.42, 5.63)

0

0.81

     

0

0.72

Complication

      

 Cerebral haemorrhage

8

7419

1.96 (0.83, 4.64)

1.44 (1.03, 2.02)

63

0.01

 Cerebral infarction

12

7635

1.07 (0.69, 1.66)

0.96 (0.74, 1,23)

39

0.08

 Neurological complication

11

7661

1.94 (1.09-3.47)

1.38 (1.12, 1.71)

58

0.009

 Cardiac complication

6

7067

2.51 (1.15. 5.50)

2.51 (1.15. 5.50)

0

0.98

  1. Abbreviations: OR, odds ratio; CI, confidence interval; mRS, modified Rankin Scale; GOS, Glasgow Outcome Scale; *Values for a random-effects model are reported.