From: Lipid management in the prevention of stroke: a meta-analysis of fibrates for stroke prevention
Source | Triglyceride lowering | Total cholesterol lowering | Relative risk (RR) and 95% CI for stroke | Relative risk (RR) and 95% CI for fatal stroke |
---|---|---|---|---|
BIP study [8] (2000) | 11.0% | 3.0% | 0.93 (0.68, 1.27) | - |
VA-HIT study [10] (1999) | 31.0% | 4.0% | 0.73 (0.53, 1.00) | 0.33 (0.09, 1.23) |
Acheson J [17] (1972) | NR | 6.4% | 1.07 (0.70, 1.63) | 0.41 (0.08, 2.00) |
Veterans Administration Cooperative Study Group [18] (1973) | 33.2% | 3.7% | 1.58 (0.97, 2.59) | 0.70 (0.23, 2.19) |
Coronary Drug Project Research Group [19] (1975) | 22.3% | 6.5% | 1.11 (0.92, 1.34) | - |
WHO-COOP committee of principal Investigators [20] (1978) | NR | 9.0% | 1.18 (0.71, 1.96) | 0.99 (0.47, 2.08) |
23.4% | 8.1% | 1.23 (0.85, 1.77) | 1.45 (0.62, 3.37) | |
E J Whitney [23] (2005) | 21.5% | 6.8% | 0.90 (0.73, 1.12) | - |
FIELD study [24] (2005) | 49.8% | 19.6% | 0.20 (0.01, 4.15) | - |
The ACCORD Study Group [25] (2010) | 15.6% | NR | 1.06 (0.72, 1.56) | 0.50 (0.15, 1.65) |