Figure 5From: Structural equation modeling of factors contributing to quality of life in Japanese patients with multiple sclerosis Causal and mutual relationships with FAMS general contentment score. The standardized total effect of EDSS on FAMS general contentment score is -.19, which consists of a standardized direct effect of -.09 and a standardized indirect effect of -.10. Changes in employment status and EDSS scores negatively affect the NAS-J anxiety/depression, acceptance, and self-esteem scores, whereas knowledge of disease information positively affects these subscales. Number of sources of disease information positively affects the NAS-J locus of control and self-efficacy scores. Changes in employment status, knowledge of disease information, number of sources of disease information, and EDSS scores affect the FAMS general contentment score indirectly through these NAS-J subscales. d1, d2, e1, e2, e3, e4, e5, and e6 in the figure are error terms. Numbers are standardized path coefficients, and asterisks (*) indicate statistical significance (p < 0.05).Back to article page