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Figure 2 | BMC Neurology

Figure 2

From: Passively transferred human NMO-IgG exacerbates demyelination in mouse experimental autoimmune encephalomyelitis

Figure 2

Spinal cord sections from mouse 24 hours after 4 injections of NMO-IgG on days 13, 14, 18, and 19 (A) versus control IgG (B) showing NMO-IgG penetration into the parenchyma of the spinal cord as shown by anti-human IgG staining (green). Sections were costained with anti-human IgG (green, C), anti-AQP4 antibody (red, D) showing co-localization in areas of AQP4 expression especially around blood vessels (arrow in merged image, E).

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BMC Neurology

ISSN: 1471-2377

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