From: A prospective cohort study of prognosis for newly diagnosed epilepsy in east China
Parameter | Outcome | Univariate comparison | |||
---|---|---|---|---|---|
Poor (N = 23) | Good (N= 157) | OR | 95% CI | P value | |
Male gender | 11 (47.8%) | 83 (52.9%) | 0.817 | 0.34 – 1.963 | 0.652 |
Age at the seizure onset | 12 (4 – 30) | 13 (1 – 65) | 1.012 | 0.967 – 1.059 | 0.598 |
>1 seizure monthly before treatment | 4 (17.4%) | 26 (16.6%) | 1.061 | 0.333 – 3.375 | 0.920 |
≥50% seizures during sleep | 12 (52.5%) | 81 (51.6%) | 1.024 | 0.426 – 2.458 | 0.958 |
Focal seizures | 18 (78.3%) | 83 (52.9%) | 3.21 | 1.135 – 9.073 | 0.028 |
Multiple seizure types | 10 (43.5%) | 27 (17.2%) | 3.704 | 1.472 – 9.319 | 0.005 |
Changes in seizure type during treatment | 3 (13.0%) | 3 (1.9%) | 7.70 | 1.454 – 40.77 | 0.016 |
Genetic epilepsy | 9 (39.1%) | 38 (24.2%) | 2.013 | 0.807 – 5.019 | 0.133 |
Positive family history | 2 (8.7%) | 14 (8.9%) | 0.973 | 0.206 – 4.587 | 0.972 |
Abnormal perinatal history | 3 (13.0%) | 11 (7.0%) | 1.991 | 0.511 – 7.753 | 0.321 |
History of brain injury | 1 (4.3%) | 9 (5.7%) | 0.747 | 0.09 – 6.19 | 0.787 |
Febrile seizures | 4 (17.4%) | 24 (15.3%) | 1.167 | 0.365 – 3.731 | 0.795 |
Mental retardation | 1 (4.3%) | 4 (2.5%) | 1.739 | 0.186 – 16.27 | 0.628 |
Abnormal neuroimaging | 3 (13.0%) | 20 (12.7%) | 1.027 | 0.28 – 3.774 | 0.967 |
EEG abnormalities characterized by an epileptiform wave | 17 (73.9%) | 82 (52.2%) | 2.591 | 0.971 – 6.919 | 0.057 |
Abnormal EEG characterized by a slow wave | 8 (34.8%) | 39 (24.8%) | 1.614 | 0.636 – 4.095 | 0.314 |