Table 1 Baseline characteristics of patients with/without hemorrhagic transformation
From: Paradoxical effect of obesity on hemorrhagic transformation after acute ischemic stroke
Hemorrhagic transformation | Pvalue* | ||
|---|---|---|---|
Absent (n = 306) | Present (n = 59) | ||
Demographic | |||
Age, y | 64.4 ± 12.4 | 66.3 ± 9.1 | 0.28 |
Gender, male | 209 (68.3%) | 37 (62.7%) | 0.45 |
Body-mass index, kg/m2† | 24.2 ± 3.2 | 23.1 ± 4.2 | 0.02 |
Clinical | |||
Hypertension | 182 (59.3%) | 37 (62.7%) | 0.67 |
Diabetes | 93 (30.4%) | 17 (28.8%) | 0.88 |
Hyperlipidemia | 47 (15.4%) | 5 (8.5%) | 0.22 |
Smoking | 0.95 | ||
Never | 192 (62.7%) | 37 (62.7%) | |
Past | 51 (16.7%) | 9 (15.3%) | |
Current | 63 (20.6%) | 13 (22%) | |
Previous use of antiplatelet agents | 9 (2.9%) | 2 (3.4%) | 0.69 |
Previous use of anticoagulation | 9 (2.9%) | 2 (3.4%) | 0.69 |
Initial NIHSS score, median (IQR)† | 8 (4–16) | 3 (2–6) | < 0.01 |
Acute treatment | |||
Thrombolysis† | 10 (3.3%) | 14 (23.7%) | < 0.01 |
Acute heparin treatment | 98 (32%) | 21 (35.6%) | 0.65 |
Stroke subtype† | < 0.01 | ||
Large artery atherosclerosis | 135 (44.1%) | 11 (18.6%) | |
Cardioembolism | 81 (26.5%) | 30 (50.8%) | |
Undetermined | 90 (29.4%) | 18 (30.5%) | |
Laboratory | |||
Glucose, mmol/L | 6.5 ± 2.1 | 6.9 ± 2.3 | 0.14 |
Total cholesterol, mmol/L | 4.6 ± 1.0 | 4.6 ± 1.0 | 0.64 |
Systolic blood pressure, mmHg | 152 ± 25 | 153 ± 27 | 0.87 |
Diastolic blood pressure, mmHg | 88 ± 15 | 90 ± 17 | 0.39 |
Prolonged PT/aPTT (%) | 36 (11.8%) | 8 (13.6%) | 0.66 |
Radiological | |||
Advanced WMLs | 76 (25.2%) | 16 (28.1%) | 0.63 |
Presence of microbleeds | 68 (22.7%) | 15 (26.3%) | 0.61 |