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Table 1 Baseline characteristics of patients with/without hemorrhagic transformation

From: Paradoxical effect of obesity on hemorrhagic transformation after acute ischemic stroke

  Hemorrhagic transformation Pvalue*
  Absent (n = 306) Present (n = 59)  
Demographic    
  Age, y 64.4 ± 12.4 66.3 ± 9.1 0.28
  Gender, male 209 (68.3%) 37 (62.7%) 0.45
  Body-mass index, kg/m2 24.2 ± 3.2 23.1 ± 4.2 0.02
Clinical    
  Hypertension 182 (59.3%) 37 (62.7%) 0.67
  Diabetes 93 (30.4%) 17 (28.8%) 0.88
  Hyperlipidemia 47 (15.4%) 5 (8.5%) 0.22
Smoking    0.95
  Never 192 (62.7%) 37 (62.7%)  
  Past 51 (16.7%) 9 (15.3%)  
  Current 63 (20.6%) 13 (22%)  
  Previous use of antiplatelet agents 9 (2.9%) 2 (3.4%) 0.69
  Previous use of anticoagulation 9 (2.9%) 2 (3.4%) 0.69
  Initial NIHSS score, median (IQR)† 8 (4–16) 3 (2–6) < 0.01
Acute treatment    
  Thrombolysis† 10 (3.3%) 14 (23.7%) < 0.01
  Acute heparin treatment 98 (32%) 21 (35.6%) 0.65
Stroke subtype†    < 0.01
  Large artery atherosclerosis 135 (44.1%) 11 (18.6%)  
  Cardioembolism 81 (26.5%) 30 (50.8%)  
  Undetermined 90 (29.4%) 18 (30.5%)  
Laboratory    
  Glucose, mmol/L 6.5 ± 2.1 6.9 ± 2.3 0.14
  Total cholesterol, mmol/L 4.6 ± 1.0 4.6 ± 1.0 0.64
  Systolic blood pressure, mmHg 152 ± 25 153 ± 27 0.87
  Diastolic blood pressure, mmHg 88 ± 15 90 ± 17 0.39
  Prolonged PT/aPTT (%) 36 (11.8%) 8 (13.6%) 0.66
Radiological    
  Advanced WMLs 76 (25.2%) 16 (28.1%) 0.63
  Presence of microbleeds 68 (22.7%) 15 (26.3%) 0.61
  1. Values are mean ± SD or number of participants (percentage).
  2. NIHSS indicates National Institute of Health Stroke Scale; WMLs, white matter lesion; and IQR, Interquartile range.
  3. *P values were obtained using the χ2 test for categorical data, and the Student t test for continuous data.
  4. P < 0.05.