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Table 1 Genotypic and allelic distributions of FBXO42 variants in PD patients and control subjects

From: Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson’s disease

Variants

Amino acid change

Genotype/Allele

N (%)

P-value (χ2)

P-value (χ2)

OR (95% CI)

Cases

Controls

rs2273311

p.S5S

GG

31 (9.81)

26 (8.81)

   
  

GA

138 (43.67)

126 (42.71)

   
  

AA

147 (46.52)

143 (48.48)

0.85 (0.32)

  
  

G

200 (31.65)

178 (30.17)

   
  

A

432 (68.35)

412 (69.83)

 

0.58 (0.31)

1.07 (0.84-1.37)

rs12069239

p.P471A

CC

219 (69.30)

191 (64.75)

   
  

CG

92 (29.11)

93 (31.53)

   
  

GG

5 (1.59)

11 (3.72)

0.18 (3.45)

  
  

C

530 (83.86)

475 (81.51)

   
  

G

102 (16.14)

115 (19.49)

 

0.13 (2.35)

1.26 (0.94-1.69)

rs35196193

p.A509T

GG

294 (93.04)

268 (90.85)

   
  

GA

20 (6.33)

27 (9.15)

   
  

AA

2 (0.63)

0 (0.00)

0.16 (3.15)

  
  

G

608 (96.20)

563 (95.42)

   
  

A

24 (3.80)

27 (4.58)

 

0.50 (0.46)

1.22 (0.69-2.13)

  1. OR, Odds ratio; CI, confidence interval.