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Table 2 Regions of statistically significant lower GMV in chronic COI patients compared to those of controls

From: Structural and cognitive deficits in chronic carbon monoxide intoxication: a voxel-based morphometry study

Gray matter volume Anatomical regions x y z Brodmann’s area Cluster size T value
Normal > All patients L Lateral Globus Pallidus −12 8 2 - 616 5.22
  L Claustrum −24 21 2 - 813 5.18
  R Amygdala 26 −9 −15 - 676 4.97
  R Caudate Body 9 14 8 - 374 4.78
  L Hippocampus −33 −14 −15 - 291 4.75
  R Putamen 27 20 5 - 540 4.47
  R Supra-marginal Gyrus 50 −42 41 40 198 4.31
  L Superior Frontal Gyrus −21 54 24 9 218 4.31
  L Post-central Gyrus −41 −23 42 2 290 4.2
  L Hypothalamus 0 −6 −11 - 283 4.18
Normal > Chronic L Post-central Gyrus −42 −23 41 2 51 3.86
Normal > Delay L Claustrum* −24 21 2 - 2116 5.88
  R Amygdala* 29 −9 −17 - 1177 5.81
  R Caudate Body 9 14 6 - 1192 5.14
  L Hippocampus −33 −12 −15 - 488 4.8
  R Inferior Parietal Lobule 51 −44 41 40 233 4.35
  L Superior Frontal Gyrus −23 54 26 9 194 3.98
  L Medial Frontal Gyrus −2 56 9 9 120 3.9
  R Anterior Cingulate 8 48 −8 32 119 3.66
  L Post-central Gyrus −38 −21 53 3 80 3.62
  L Mammillary Body 2 −8 −11 - 63 3.59
Chronic > Delay L Anterior Cingulate −2 48 −11 32 2301 5.06
  R Amygdala 29 −11 −18 - 112 3.73
  1. Voxel-based morphometry of COI patients compared to those of normal controls at an uncorrected p value (<0.001).
  2. * Indicated for statistical threshold: uncorrected p < 0.001 with a cluster extent correction FWE-corrected p value < 0.05.
  3. (x, y, and z) refer to the Montreal Neurological Institute coordinates. The T-value is determined by dividing the estimated regression coefficient by its standard error.
  4. Abbreviations: R Right; L Left.