TY - JOUR AU - Riba-Llena, Iolanda AU - Jarca, Carmen Ioana AU - Mundet, Xavier AU - Tovar, Jose L. AU - Orfila, Francesc AU - López-Rueda, Antonio AU - Nafría, Cristina AU - Fernández, Jose L. AU - Castañé, Xavier AU - Domingo, Mar AU - Álvarez-Sabín, José AU - Fernández-Cortiñas, Inés AU - Maisterra, Olga AU - Montaner, Joan AU - Delgado, Pilar PY - 2013 DA - 2013/10/02 TI - Investigating silent strokes in hypertensives: a magnetic resonance imaging study (ISSYS): rationale and protocol design JO - BMC Neurology SP - 130 VL - 13 IS - 1 AB - Silent brain infarcts are detected by neuroimaging in up to 20% of asymptomatic patients based on population studies. They are five times more frequent than stroke in general population, and increase significantly both with advancing age and hypertension. Moreover, they are independently associated with the risk of future stroke and cognitive decline. SN - 1471-2377 UR - https://doi.org/10.1186/1471-2377-13-130 DO - 10.1186/1471-2377-13-130 ID - Riba-Llena2013 ER -