Figure 1From: Lovastatin improves impaired synaptic plasticity and phasic alertness in patients with neurofibromatosis type 1 Synaptic plasticity in patients with NF1 and controls. A) Depicted is the time course of MEP amplitudes after PAS in healthy controls and patients with NF1. PAS led to a significant MEP increase only in the control group. Abscissa pictures point in time and ordinate mean MEP amplitude. Asterisks indicate significant differences between two groups or points in time (p < 0.05, unpaired t test), error bars represent ± standard error of the mean. B) MEP amplitudes from two representative subjects of controls and NF1before and at POST 1 after PAS. Shown are averages of 20 MEP trials in each case.Back to article page