Variables | CRPS (n=17) | Patients with peripheral nerve injury (n=17) | Pain-free controls (n= 22) |
---|---|---|---|
Gender (female, n (%)) | 8 (47%) | 11 (65%) | 12 (55%) |
Age (years) | 53 ± 14 | 53 ± 14 | 52 ± 13 |
Affected side (right), n (%) | 11 (66%) | 10 (60%) | |
Diagnosis, n (%) | CRPS I, 17 (100%) | Neuralgia of median nerve, 6 (36%) | |
Neuralgia of ulnar nerve, 5 (30%) | |||
Neuralgia of radial nerve, 5 (30%) | |||
Neuralgia of median, ulnar, radial nerve, 1 (6%) | |||
Precipitating event, n (%) | |||
Fracture | 6 (36%) | 1 (6%) | |
Crush injury | 4 (24%) | 8 (48%) | |
Surgery | 6 (36%) | 4 (24%) | |
Carpal tunnel syndrome | - | 4 (24%) | |
Other | 1 (6%) | - | |
Current analgesics, n° | |||
No medication | 4 (24%) | 7 (42%) | |
Opioids | 7 (42%) | 6 (36%) | |
Tricyclic Antidrepressants | 3 (18%) | 6 (36%) | |
Anticonvulsants | 6 (36%) | 8 (48%) | |
Coxibs | 5 (30%) | 2 (12%) | |
Other non-opioid analgesics | 9 (54%) | 4 (24%) | |
Cardiovascular risk factors, n (%)° | |||
Current smoker | 4 (24%) | 6 (36%) | 5 (23%) |
Past smoker | 3 (18%) | 3 (18%) | 2 (9%) |
Arterial hypertension | 3 (18%) | 5 (30%) | 3 (14%) |
Diabetes mellitus | |||
Typ I | - | 2 (12%) | - |
Typ II | 1 (6%) | 1 (6%) | 1 (5%) |
Hypercholesterolemia | 1 (6%) | 2 (12%) | 1 (5%) |
Patients with cardiovascular risk factors, n (%) | |||
None | 6 (36%) | 5 (30%) | 11 (50%) |
One factor | 10 (60%) | 6 (36%) | 10 (45%) |
Two factors | 1 (6%) | 5 (30%) | 1 (5%) |
Three factors | - | 1 (6%) | - |
Pain duration (months) | 16 ± 13 (4…60)# | 97 ± 12 (4…360)# | |
Patients < 12 months pain duration, n (%) | 10 (60%) # | 1 (6%) # | |
Current pain intensity (examination day, NRS 0–10) | 4 ± 0 | 5 ± 4 | |
Maximal pain intensity (examination day, NRS 0–10) | 6 ± 4 | 7 ± 4 | |
Patients with positive symptom categories, n (%) ° * | |||
Sensory | 14 (82%) | 13 (77%) | |
Vasomotor | 11 (65%) | 8 (48%) | |
Sudomotor/edema | 14 (82%) | 7 (42%) | |
Motor/trophic | 17 (100%) | 15 (90%) | |
Patients with positive sign categories, n (%) ° * | |||
Sensory | 13 (78%) | 12 (72%) | |
Vasomotor | 11 (66%) | 7 (42%) | |
Sudomotor/edema | 14 (82%) | 5 (30%) | |
Motor/trophic | 17 (100%) | 15 (88%) |