Skip to main content

Table 1 Clinical data

From: Morphological macrovascular alterations in complex regional pain syndrome type I demonstrated by increased intima-media thickness

Variables

CRPS (n=17)

Patients with peripheral nerve injury (n=17)

Pain-free controls (n= 22)

Gender (female, n (%))

8 (47%)

11 (65%)

12 (55%)

Age (years)

53 ± 14

53 ± 14

52 ± 13

Affected side (right), n (%)

11 (66%)

10 (60%)

 

Diagnosis, n (%)

CRPS I, 17 (100%)

Neuralgia of median nerve, 6 (36%)

 
  

Neuralgia of ulnar nerve, 5 (30%)

 
  

Neuralgia of radial nerve, 5 (30%)

 
  

Neuralgia of median, ulnar, radial nerve, 1 (6%)

 

Precipitating event, n (%)

   

  Fracture

6 (36%)

1 (6%)

 

  Crush injury

4 (24%)

8 (48%)

 

  Surgery

6 (36%)

4 (24%)

 

  Carpal tunnel syndrome

-

4 (24%)

 

  Other

1 (6%)

-

 

Current analgesics, n°

   

  No medication

4 (24%)

7 (42%)

 

  Opioids

7 (42%)

6 (36%)

 

  Tricyclic Antidrepressants

3 (18%)

6 (36%)

 

  Anticonvulsants

6 (36%)

8 (48%)

 

  Coxibs

5 (30%)

2 (12%)

 

  Other non-opioid analgesics

9 (54%)

4 (24%)

 

Cardiovascular risk factors, n (%)°

   

  Current smoker

4 (24%)

6 (36%)

5 (23%)

  Past smoker

3 (18%)

3 (18%)

2 (9%)

  Arterial hypertension

3 (18%)

5 (30%)

3 (14%)

  Diabetes mellitus

   

  Typ I

-

2 (12%)

-

  Typ II

1 (6%)

1 (6%)

1 (5%)

  Hypercholesterolemia

1 (6%)

2 (12%)

1 (5%)

Patients with cardiovascular risk factors, n (%)

   

  None

6 (36%)

5 (30%)

11 (50%)

  One factor

10 (60%)

6 (36%)

10 (45%)

  Two factors

1 (6%)

5 (30%)

1 (5%)

  Three factors

-

1 (6%)

-

Pain duration (months)

16 ± 13 (4…60)#

97 ± 12 (4…360)#

 

Patients < 12 months pain duration, n (%)

10 (60%) #

1 (6%) #

 

Current pain intensity (examination day, NRS 0–10)

4 ± 0

5 ± 4

 

Maximal pain intensity (examination day, NRS 0–10)

6 ± 4

7 ± 4

 

Patients with positive symptom categories, n (%) ° *

   

Sensory

14 (82%)

13 (77%)

 

Vasomotor

11 (65%)

8 (48%)

 

Sudomotor/edema

14 (82%)

7 (42%)

 

Motor/trophic

17 (100%)

15 (90%)

 

Patients with positive sign categories, n (%) ° *

   

  Sensory

13 (78%)

12 (72%)

 

  Vasomotor

11 (66%)

7 (42%)

 

  Sudomotor/edema

14 (82%)

5 (30%)

 

  Motor/trophic

17 (100%)

15 (88%)

 
  1. Numeric values are in mean ± SD (range). Percentage values refer to the columns. # p<0.001 (Mann–Whitney U-test). CRPS: complex regional pain syndrome; NRS: numeric rating scala. ° Multiple answers possible. * According to the Budapest-criteria [1].