Extent of cortical involvement in amyotrophic lateral sclerosis – an analysis based on cortical thickness

BMC Neurology

Table 1 Clinical data

Pat.	Age	Sex	Dur.	RUE (75)	LUE (75)	RLE (45)	LLE (45)	Bulbar (0–14)	Babinski (0–2)	Spasticity (0–32)	Reflexes (0–13)	ALSFRS-R	ALSFRS-R PR/M6	ALSFRS-R PR/M(t)
1	59	m	30	68	69	41	41	2	0	0	0	43	0.5	0.2
2	59	m	13	75	64	31	27	0	0	0	0	37	1.8	0.8
3	31	m	17	64	62	45	45	0	2	0	12	42	1.2	0.4
4	68	m	22	75	73	45	42	2	2	4	4	40	0.7	0.4
5	65	m	25	72	75	26	16	0	1	0	6	37	0.7	0.4
6	53	m	38	74	75	26	23	0	0	0	0	43	0.2	0.1
7	34	w	18	70	71	45	45	4	2	0	12	39	1.0	0.5
8	62	m	18	63	73	45	45	4	0	0	12	40	0.7	0.4
9	49	m	19	54	55	45	45	0	2	0	0	41	0.3	0.4
10	60	m	30	58	57	45	45	2	2	0	5	33	1.5	0.5
11	77	m	34	70	71	22	37	0	2	2	12	33	1.7	0.4
12	63	w	12	75	75	45	45	3	0	0	11	45	0.2	0.3
13	66	m	23	61	71	44	44	0	1	0	0	48	0.0	0.0
14	72	m	25	69	71	40	41	3	2	4	6	48	1.0	0.3

Pat. = patient; Dur. = duration in months; m = man, w = woman; RUE, LUE, RLE, LLE: right upper, left upper, right lower, left lower extremity; ALSFRS-R: ALS functional rating scale- revised, PR/M6 progression rate for the 6 months prior to MR-scanning, PR/M(t) progression rate per month for the entire duration of the disease.

ISSN: 1471-2377

Pat.	Age	Sex	Dur.	RUE (75)	LUE (75)	RLE (45)	LLE (45)	Bulbar (0–14)	Babinski (0–2)	Spasticity (0–32)	Reflexes (0–13)	ALSFRS-R	ALSFRS-R PR/M6	ALSFRS-R PR/M(t)
1	59	m	30	68	69	41	41	2	0	0	0	43	0.5	0.2
2	59	m	13	75	64	31	27	0	0	0	0	37	1.8	0.8
3	31	m	17	64	62	45	45	0	2	0	12	42	1.2	0.4
4	68	m	22	75	73	45	42	2	2	4	4	40	0.7	0.4
5	65	m	25	72	75	26	16	0	1	0	6	37	0.7	0.4
6	53	m	38	74	75	26	23	0	0	0	0	43	0.2	0.1
7	34	w	18	70	71	45	45	4	2	0	12	39	1.0	0.5
8	62	m	18	63	73	45	45	4	0	0	12	40	0.7	0.4
9	49	m	19	54	55	45	45	0	2	0	0	41	0.3	0.4
10	60	m	30	58	57	45	45	2	2	0	5	33	1.5	0.5
11	77	m	34	70	71	22	37	0	2	2	12	33	1.7	0.4
12	63	w	12	75	75	45	45	3	0	0	11	45	0.2	0.3
13	66	m	23	61	71	44	44	0	1	0	0	48	0.0	0.0
14	72	m	25	69	71	40	41	3	2	4	6	48	1.0	0.3

Pat.	Age	Sex	Dur.	RUE (75)	LUE (75)	RLE (45)	LLE (45)	Bulbar (0–14)	Babinski (0–2)	Spasticity (0–32)	Reflexes (0–13)	ALSFRS-R	ALSFRS-R PR/M6	ALSFRS-R PR/M(t)
1	59	m	30	68	69	41	41	2	0	0	0	43	0.5	0.2
2	59	m	13	75	64	31	27	0	0	0	0	37	1.8	0.8
3	31	m	17	64	62	45	45	0	2	0	12	42	1.2	0.4
4	68	m	22	75	73	45	42	2	2	4	4	40	0.7	0.4
5	65	m	25	72	75	26	16	0	1	0	6	37	0.7	0.4
6	53	m	38	74	75	26	23	0	0	0	0	43	0.2	0.1
7	34	w	18	70	71	45	45	4	2	0	12	39	1.0	0.5
8	62	m	18	63	73	45	45	4	0	0	12	40	0.7	0.4
9	49	m	19	54	55	45	45	0	2	0	0	41	0.3	0.4
10	60	m	30	58	57	45	45	2	2	0	5	33	1.5	0.5
11	77	m	34	70	71	22	37	0	2	2	12	33	1.7	0.4
12	63	w	12	75	75	45	45	3	0	0	11	45	0.2	0.3
13	66	m	23	61	71	44	44	0	1	0	0	48	0.0	0.0
14	72	m	25	69	71	40	41	3	2	4	6	48	1.0	0.3

Pat.	Age	Sex	Dur.	RUE (75)	LUE (75)	RLE (45)	LLE (45)	Bulbar (0–14)	Babinski (0–2)	Spasticity (0–32)	Reflexes (0–13)	ALSFRS-R	ALSFRS-R PR/M6	ALSFRS-R PR/M(t)
1	59	m	30	68	69	41	41	2	0	0	0	43	0.5	0.2
2	59	m	13	75	64	31	27	0	0	0	0	37	1.8	0.8
3	31	m	17	64	62	45	45	0	2	0	12	42	1.2	0.4
4	68	m	22	75	73	45	42	2	2	4	4	40	0.7	0.4
5	65	m	25	72	75	26	16	0	1	0	6	37	0.7	0.4
6	53	m	38	74	75	26	23	0	0	0	0	43	0.2	0.1
7	34	w	18	70	71	45	45	4	2	0	12	39	1.0	0.5
8	62	m	18	63	73	45	45	4	0	0	12	40	0.7	0.4
9	49	m	19	54	55	45	45	0	2	0	0	41	0.3	0.4
10	60	m	30	58	57	45	45	2	2	0	5	33	1.5	0.5
11	77	m	34	70	71	22	37	0	2	2	12	33	1.7	0.4
12	63	w	12	75	75	45	45	3	0	0	11	45	0.2	0.3
13	66	m	23	61	71	44	44	0	1	0	0	48	0.0	0.0
14	72	m	25	69	71	40	41	3	2	4	6	48	1.0	0.3