Multimodal noninvasive and invasive imaging of extracranial venous abnormalities indicative of CCSVI: Results of the PREMiSe pilot study

Table 5 Comparison of catheter venography (as "gold standard/benchmark") for the detection of abnormal findings in the internal jugular veins and in azygos vein/vertebral veins using intravascular ultrasound

Catheter venography	# of positive cases	Noninvasive and invasive imaging modalities	# of positive cases	Total # of cases	Sensitivity	Specificity	PPV	NPV	OR
IJV right	11	IVUS IJV right	10	20	72.7	77.8	80	70	9.33 (1.19-72.99)
IJV left	13	IVUS IJV left	15	18	84.6	20	73.3	33.3	1.38 (.10-19.64)
IJVs total	17	IVUS IJV total	18	20	88.2	0	83.3	0	1.20 (.98-1.48)
Azygos total	10	IVUS azygos total	17	20	90	20	52.9	66.7	2.25 (.17-29.77)

Legend: IJVs - internal jugular veins; VVs - vertebral veins; D; OR -odds ratio. Nineteen and 18 patients successfully obtained CV and IVUS in the left IJV, respectively (because of difficulty to access with the wire). All 20 patients successfully obtained other noninvasive and invasive examinations in the explored vein territories. Therefore, for the left IJVs comparisons with CV and IVUS, only data from 19 and 18 patients were used.

ISSN: 1471-2377