Multimodal noninvasive and invasive imaging of extracranial venous abnormalities indicative of CCSVI: Results of the PREMiSe pilot study

Table 6 Comparison of Doppler sonography and magnetic resonance venography (combined as the "gold standard/benchmark") for the detection of abnormal findings in the internal jugular veins and in azygos vein/vertebral veins using other invasive imaging techniques

DS + MRV	# of positive cases	Noninvasive and invasive imaging modalities	# of positive cases	Total # of cases	Sensitivity
IJV right	19	CV IJV right	11	20	57.9
		IVUS IJV right	10		52.6
		CV + IVUS IJV right	13		68.4
IJV left	20	CV IJV left	14	19	73.7
		IVUS IJV left	15	18	83.3
		CV + IVUS IJV left	18	18	NA*
IJVs total	20	CV IJV total	17	20	85
		IVUS IJV total	18		90
		CV + IVUS IJV total	20		NA*
VVs total	8	CV azygos total	10	20	25
VVs total	8	IVUS azygos total	17	20	87.5
		CV + IVUS azygos total	18		87.5

Legend: IJV(s) - internal jugular vein(s); VVs - vertebral veins; MRV - magnetic resonance venography; CV - catheter venography; IVUS - intravascular ultrasound.
Nineteen and18 patients successfully obtained CV and IVUS in the left IJV, respectively (because of difficulty to access with the wire). All 20 patients successfully obtained other noninvasive and invasive examinations in the explored vein territories. Therefore, for the left IJVs comparisons with CV and IVUS, only data from 19 and 18 patients were used.
*The SPSS does not provide an estimate of odds ratio or its confidence interval whenever there is a zero count in the contingency table. Instead, it returns an estimate of relative risk. Therefore those results are reported as "not available".

ISSN: 1471-2377