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Table 1 Patients’ demographic and risk factor characteristics

From: Higher numbers of circulating endothelial progenitor cells in stroke patients with intracranial arterial stenosis

  HC (n = 72) CP (n = 120) IAS (n = 108) PΔ P# P *
Age, mean ± SD 56.0 ± 10.2 56.9 ± 7.6 61.5 ± 12.1 0.652 0.132 0.281
Gender (female), n (%) 28 (38.9) 48 (40.0) 48 (44.4) 0.879 0.460 0.497
BMI, Kg/m2 24.2 ± 4.2 26.1 ± 8.6 26.9 ± 8.9 0.035 0.031 0.756
sBP, mmHg 123.2 ± 17.7 134.1 ± 16.54 138.1 ± 18.72 0.065 0.036 0.452
dBP, mmHg 81.6 ± 10.1 83.52 ± 12.05 85.6 ± 10.1 0.396 0.041 0.462
TG, mmol/l 1.325 ± 0.35 1.446 ± 0.77 1.504 ± 0.83 0.689 0.478 0.837
TC, mmol/l 3.935 ± 0.93 4.078 ± 0.68 4.697 ± 0.85 0.696 0.019 0.089
HDL, mmol/l 1.198 ± 0.26 1.05 ± 0.16 0.955 ± 0.15 0.099 0.003 0.297
LDL, mmol/l 2.43 ± 0.81 2.626 ± 0.55 2.624 ± 0.78 0.623 0.601 0.991
Glu, mmol/l 5.75 ± 1.06 6.059 ± 3.32 5.58 ± 0.97 0.745 0.748 0.555
CRP, mg/l 0.65 (0.31-1.37) 1.55 (0.65-2.71) 2.75(1.2-3.25) 0.021 <0.001 0.012
Hypertension, n (%) 0 30 (25.0) 84 (77.8) - - <0.001
cEPCs (%)       
  CD34+ 0.293 ± 0.182 0.364 ± 0.201 0.553 ± 0.311 0.028 0.009 0.019
  CD34+/CD133+ 0.098 ± 0.032 0.113 ± 0.064 0.246 ± 0.142 0.382 <0.001 <0.001
  CD34+/CD133+/KDR+ 0.021 ± 0.011 0.026 ± 0.012 0.059 ± 0.031 0.401 <0.001 <0.001
Diabetes, n (%) 0 6 (5.0) 24 (22.2) - - <0.001
Hyperlipidemia, n (%) 0 18 (15.0) 24 (22.2) - - 0.160
CAD, n (%) 0 12 (10.0) 18 (16.7) - - 0.137
Smoking, n (%) 0 48 (40.0) 78 (72.2) - - <0.001
Drug treatment     - -  
  Statin, n (%) 4 (5) 31 (26) 35 (32) - - 0.316
  ACE inhibitor, n (%) - 20 (17) 31 (29) - - 0.029
  Angiotensin II receptor blocker, n (%) - 3 (2) 2 (2) - - 0.739
  Beta blocker, n (%) - 10 (8) 13 (12) - - 0.345
  Calcium antagonist, n (%) - 19 (16) 34 (32) - - 0.005
  1. PΔ: CP vs. HC P#: IAS vs. HC P *: IAS vs. CP.
  2. sBP: systolic blood pressure; dBP: diastolic blood pressure.
  3. HC, healthy controls; CP, control patients; IAS, patients with intracranial artery stenosis; CAD: coronary artery disease.