Table 1 Overview of cohort’s clinical and visual data
Subjects | N | RRMS 89 |
|---|---|---|
Sex | Male, N (%) | 36 (40) |
Female, N (%) | 53 (60) | |
Age (years) | Mean ± SD | 42 ± 9 |
Min - Max | 25 - 62 | |
Time since diagnosis (months) | Mean ± SD | 97 ± 67 |
Min - Max | 2 - 340 | |
EDSS | Median | 2.0 |
Min - Max | 0.0 - 6.0 | |
RNFL Average (μm) | Mean ± SD | 84.5 ± 14.3 |
Min - Max | 33.2 - 117.4 | |
VA (ETDRS Snellen equivalents) | Mean ± SD | 1.05 ± 0.36 |
Min - Max | 0.20 - 1.60 | |
CS (FACT AUC) | Mean ± SD | 1.85 ± 0.32 |
Min - Max | 0.82 - 2.28 | |
Cognitively impaired (BRB-N z < 0.168) | No, N (%) | 63 (72) |
Yes, N (%) | 25 (28) | |
Fatigue severity scale (FSS) | Mean ± SD | 5.0 ± 2.5 |
Min - Max | 0.0 - 9.0 | |
Fatigued (FSS > = 4.0) | No, N (%) | 35 (39) |
Yes, N (%) | 54 (61) | |
Beck’s depression inventory (BDI) | Mean ± SD | 8.1 ± 7.9 |
Min - Max | 0 - 29 | |
Depressed (BDI > = 30; 19-29; 10-18; 0-9) | Minimal, N (%) | 60 (69) |
Mild, N (%) | 14 (16) | |
Moderate, N (%) | 13 (15) | |
Severe, N (%) | 0 (0) |