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Table 1 Parameters of cerebral vascular function (blood flow and cerebral vasomotor reactivity

From: Cerebral hemodynamics and endothelial function in patients with Fabry disease

Parameter

Healthy volunteers (n = 17)

Patients with FD (n = 10)

p value

Right middle cerebral artery

   
 

Mean blood flow velocity (cm/s)

56.07 ± 10.36

56.82 ± 15.53

0.9

 

Maximum blood flow velocity (cm/s)

87.58 ± 16.48

86.64 ± 21.66

0.9

 

Pulsatility index

0.84 ± 0.15

0.80 ± 0.18

0.57

 

Apnea Test (%)

56.79 ± 15.68

47.25 ± 15.36

0.21

Left middle cerebral artery

   
 

Mean blood flow velocity (cm/s)

59.21 ± 14.15

58.15 ± 16.95

0.9

 

Maximum blood flow velocity (cm/s)

94.30 ± 22.09

88.85 ± 26.64

0.6

 

Pulsatility index

0.89 ± 0.1402

0.83 ± 0.2161

0.4

Right anterior cerebral artery

   
 

Mean blood flow velocity (cm/s)

47.90 ± 11.82

49.18 ± 13.00

0.8

 

Maximum blood flow velocity (cm/s)

75.97 ± 16.73

74.53 ± 25.22

0.9

 

Pulsatility index

0.89 ± 0.11

0.84 ± 0.21

0.4

Left anterior cerebral artery

   
 

Mean blood flow velocity (cm/s)

48.95 ± 11.69

47.29 ± 16.57

0.8

 

Maximum blood flow velocity (cm/s)

76.66 ± 15.13

70.61 ± 25.79

0.5

 

Pulsatility index

0.87 ± 0.15

0.89 ± 0.23

0.8

Right posterior cerebral artery

   
 

Mean blood flow velocity (cm/s)

40.93 ± 8.22

37.80 ± 11.11

0.4

 

Maximum blood flow velocity (cm/s)

64.85 ± 13.19

53.55 ± 18.00

0.1

 

Pulsatility index

0.8897 ± 0.23

0.7651 ± 0.20

0.2

Left posterior cerebral artery

   
 

Mean blood flow velocity (cm/s)

37.84 ± 5.12

37.60 ± 10.11

0.9

 

Maximum blood flow velocity (cm/s)

59.41 ± 7.48

56.25 ± 17.09

0.5

 

Pulsatility index

0.86 ± 0.13

0.83 ± 0.20

0.8

Basilar artery

   
 

Mean blood flow velocity (cm/s)

41.60 ± 8.14

45.38 ± 12.90

0.4

 

Maximum blood flow velocity (cm/s)

65.35 ± 12.52

64.02 ± 25.69

0.8

 

Pulsatility index

0.86 ± 0.13

0.78 ± 0.20

0.3

  1. apnea test = breath-holding test. Data are means ± SD.