From: Cerebral hemodynamics and endothelial function in patients with Fabry disease
Parameter | Healthy volunteers (n = 17) | Patients with FD (n = 10) | pvalue |
---|---|---|---|
IMT right common carotid artery (mm) | 0.57 ± 0.07 | 0.60 ± 0.19 | 0.51 |
Distance between advential layers of right common carotid artery (mm) | 6.25 ± 1.55 | 6.50 ± 0.91 | 0.71 |
IMT left common carotid artery (mm) | 0.54 ± 0.94 | 0.62 ± 0.21 | 0.16 |
Distance between advential layers of left common carotid artery (mm) | 6.45 ± 0.78 | 6.66 ± 0.91 | 0.62 |
Mean diameter of brachial artery (mm) | 3.64 ± 0.67 | 3.38 ± 0.70 | 0.36 |
Brachial hyperaemic vasodilation test (60”) | 16.85 ± 10.59 | 14.10 ± 11.62 | 0.54 |
us-CRP (mg/L) | 1.74 ± 1.51 | 2.92 ± 1.88 | 0.14 |
IL-6 (pg/mL) | 7.48 ± 2.15 | 6.34 ± 1.42 | 0.06 |
sVCAM-1 (ng/mL) | 714.47 ± 178.22 | 899.50 ± 217.24 | 0.02 |
TNF-α (pg/mL) | 4.41 ± 1.17 | 5.41 ± 1.66 | 0.11 |