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Table 1 Demographic characteristics

From: Increased leptin and A-FABP levels in relapsing and progressive forms of MS

  Group 1 Group 2 Group 3
  Relapsing- remitting MS Primary progressive MS Secondary progressive MS Healthy controls Pediatric onset MS Pediatric healthy controls Pre- relapse patients Relapse patients
N 20 13 12 48 12 10 18 11
Males N (%) 3 (15.0) 6 (46.2) 1 (8.3) 14 (29.2) 4 (33.3) 3 (30.0) 3 (16.7) 2 (18.2)
Age Mean (SD) 43.0 (8.9) 56.9 (7.7) 53.6 (12.5) 45.1 (13.1) 13.9 (2.3) 11.4 (3.3) 40.7 (11.3) 36.4 (10.9)
Hispanic N (%) 0 (0) 0 (0) 0 (0) 0 (0) 1 (8.3) 1 (10.0) 1 (5.6) 0 (0)
White N (%) 18 (90.0) 13 (100) 12 (100) 44 (91.7) 10 (83.3) 8 (80.0) 17 (94.4) 9 (81.8)
BMI Mean (SD) 27.7 (5.0) 30.1 (5.4) 30.7 (7.9) 26.0 (6.2) 26.9 (9.2) 21.4 (3.7) 26.2 (4.4) 29.5 (6.3)
EDSS Median (Range) 2 (0–4.5) 6 (1.5-7) 5.0 (2.5-8.0)   1.75 (0–2)   1.75 (0–6) 2 (0–3.5)
Disease Duration Mean (SD) 11.3 (9.3) 14.5 (7.6) 19.9 (9.6)   1.75 (2.1)   8.1 (6.6) 8.2 (5.5)
Leptin (pg/ml) Mean (SD) 23,462.3 (27,708.9) 17,924.6 (14,009.8) 40,412.6 (27,951.8) 13,840.5 (18,447.6) 27,357.3 (20,207.4) 11,177.0 (11,484.7) 24,381.6 (20,350.1) 37,587.1 (26,465.4)
A-FABP (ng/ml) Mean (SD) 21.2 (14.6) 34.9 (18.9) 38.8 (15.5) 18.4 (18.8) 26.7 (18.0) 14.7 (7.6) 17.5 (10.5) 27.7 (13.1)
  1. Legend: MS = Multiple sclerosis, BMI = Body mass index, EDSS = Expanded disability status scale, A-FABP = adipocyte fatty acid binding protein, SD standard deviation.