Table 1 Demographic characteristics
From: Increased leptin and A-FABP levels in relapsing and progressive forms of MS
Group 1 | Group 2 | Group 3 | ||||||
|---|---|---|---|---|---|---|---|---|
Relapsing- remitting MS | Primary progressive MS | Secondary progressive MS | Healthy controls | Pediatric onset MS | Pediatric healthy controls | Pre- relapse patients | Relapse patients | |
N | 20 | 13 | 12 | 48 | 12 | 10 | 18 | 11 |
Males N (%) | 3 (15.0) | 6 (46.2) | 1 (8.3) | 14 (29.2) | 4 (33.3) | 3 (30.0) | 3 (16.7) | 2 (18.2) |
Age Mean (SD) | 43.0 (8.9) | 56.9 (7.7) | 53.6 (12.5) | 45.1 (13.1) | 13.9 (2.3) | 11.4 (3.3) | 40.7 (11.3) | 36.4 (10.9) |
Hispanic N (%) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (8.3) | 1 (10.0) | 1 (5.6) | 0 (0) |
White N (%) | 18 (90.0) | 13 (100) | 12 (100) | 44 (91.7) | 10 (83.3) | 8 (80.0) | 17 (94.4) | 9 (81.8) |
BMI Mean (SD) | 27.7 (5.0) | 30.1 (5.4) | 30.7 (7.9) | 26.0 (6.2) | 26.9 (9.2) | 21.4 (3.7) | 26.2 (4.4) | 29.5 (6.3) |
EDSS Median (Range) | 2 (0–4.5) | 6 (1.5-7) | 5.0 (2.5-8.0) | 1.75 (0–2) | 1.75 (0–6) | 2 (0–3.5) | ||
Disease Duration Mean (SD) | 11.3 (9.3) | 14.5 (7.6) | 19.9 (9.6) | 1.75 (2.1) | 8.1 (6.6) | 8.2 (5.5) | ||
Leptin (pg/ml) Mean (SD) | 23,462.3 (27,708.9) | 17,924.6 (14,009.8) | 40,412.6 (27,951.8) | 13,840.5 (18,447.6) | 27,357.3 (20,207.4) | 11,177.0 (11,484.7) | 24,381.6 (20,350.1) | 37,587.1 (26,465.4) |
A-FABP (ng/ml) Mean (SD) | 21.2 (14.6) | 34.9 (18.9) | 38.8 (15.5) | 18.4 (18.8) | 26.7 (18.0) | 14.7 (7.6) | 17.5 (10.5) | 27.7 (13.1) |