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Table 2 Alterations in plasma miRNA levels in patients with ischemic stroke compared to healthy controls

From: Circulating miR-30a, miR-126 and let-7b as biomarker for ischemic stroke in humans

 

STROKE

HA ΔCT ± SD

 

24 h

1 w

4 w

24 w

48 w

 

miR-30a

     

−6.18 ± 1.27

LA Δct ± SD

−4.42 ± 0.57

−4.12 ± 0.43

−4.53 ± 0.46

−4.65 ± 0.47

−6.02 ± 0.45

 

SA Δct ± SD

−4.15 ± 0.43

−4.36 ± 0.18

−4.63 ± 0.35

−4.38 ± 0.35

−5.97 ± 0.34

 

CEmb Δct ± SD

−4.79 ± 0.40

−4.71 ± 0.15

−5.26 ± 0.26

−5.7 ± 0.42

−6.12 ± 0.32

 

UND Δct ± SD

−3.94 ± 0.32

−4.91 ± 0.28

−5.33 ± 0.29

−4.29 ± 0.49

−6.05 ± 0.19

 

p value

0.02

0.01

0.03

0.01

0.01

 

miR-126

     

0.39 ± 0.012

LA Δct ± SD

4.51 ± 1.25

4.28 ± 1.13

3.95 ± 1.05

3.45 ± 1.03

0.41 ± 0.023

 

SA Δct ± SD

4.38 ± 1.12

4.16 ± 1.15

3.75 ± 1.12

2.95 ± 0.23

0.36 ± 0.013

 

CEmb Δct ± SD

4.57 ± 1.32

4.08 ± 0.98

3.86 ± 0.89

3.15 ± 0.43

0.37 ± 0.021

 

UND Δct ± SD

4.49 ± 1.08

4.12 ± 1.02

3.69 ± 0.97

1.98 ± 0.38

0.42 ± 0.032

 

p value

0.01

0.01

0.02

0.03

0.01

 

Let-7b

     

−11.12 ± 2.16

LA Δct ± SD

−9.12 ± 1.25

−9.36 ± 1.06

−9.28 ± 1.34

−9.31 ± 1.13

−11.15 ± 1.22

 

SA Δct ± SD

−13.98 ± 2.15

−14.18 ± 1.32

−13.46 ± 1.45

−13.12 ± 1.42

−11.01 ± 1.08

 

CEmb Δct ± SD

−14.36 ± 2.18

−14.78 ± 1.95

−14.12 ± 1.53

−13.92 ± 1.67

−10.93 ± 1.52

 

UND Δct ± SD

−14.23 ± 1.58

−14.97 ± 1.78

−14.67 ± 1.36

−12.93 ± 1.76

−10.96 ± 1.63

 

p value

0.01

0.02

0.01

0.01

0.01

 
  1. Δct value of miR-126, miR-30a and let-7b in ischemic stroke groups and healthy adult. SD stands for the standard deviation of the average Δct of the group. Corresponding p values were calculated using the Independent-samples T test. HA Δct ± SD stands for Δct ± SD of healthy adult.