Skip to main content

Table 2 Alterations in plasma miRNA levels in patients with ischemic stroke compared to healthy controls

From: Circulating miR-30a, miR-126 and let-7b as biomarker for ischemic stroke in humans

  STROKE HA ΔCT ± SD
  24 h 1 w 4 w 24 w 48 w  
miR-30a       −6.18 ± 1.27
LA Δct ± SD −4.42 ± 0.57 −4.12 ± 0.43 −4.53 ± 0.46 −4.65 ± 0.47 −6.02 ± 0.45  
SA Δct ± SD −4.15 ± 0.43 −4.36 ± 0.18 −4.63 ± 0.35 −4.38 ± 0.35 −5.97 ± 0.34  
CEmb Δct ± SD −4.79 ± 0.40 −4.71 ± 0.15 −5.26 ± 0.26 −5.7 ± 0.42 −6.12 ± 0.32  
UND Δct ± SD −3.94 ± 0.32 −4.91 ± 0.28 −5.33 ± 0.29 −4.29 ± 0.49 −6.05 ± 0.19  
p value 0.02 0.01 0.03 0.01 0.01  
miR-126       0.39 ± 0.012
LA Δct ± SD 4.51 ± 1.25 4.28 ± 1.13 3.95 ± 1.05 3.45 ± 1.03 0.41 ± 0.023  
SA Δct ± SD 4.38 ± 1.12 4.16 ± 1.15 3.75 ± 1.12 2.95 ± 0.23 0.36 ± 0.013  
CEmb Δct ± SD 4.57 ± 1.32 4.08 ± 0.98 3.86 ± 0.89 3.15 ± 0.43 0.37 ± 0.021  
UND Δct ± SD 4.49 ± 1.08 4.12 ± 1.02 3.69 ± 0.97 1.98 ± 0.38 0.42 ± 0.032  
p value 0.01 0.01 0.02 0.03 0.01  
Let-7b       −11.12 ± 2.16
LA Δct ± SD −9.12 ± 1.25 −9.36 ± 1.06 −9.28 ± 1.34 −9.31 ± 1.13 −11.15 ± 1.22  
SA Δct ± SD −13.98 ± 2.15 −14.18 ± 1.32 −13.46 ± 1.45 −13.12 ± 1.42 −11.01 ± 1.08  
CEmb Δct ± SD −14.36 ± 2.18 −14.78 ± 1.95 −14.12 ± 1.53 −13.92 ± 1.67 −10.93 ± 1.52  
UND Δct ± SD −14.23 ± 1.58 −14.97 ± 1.78 −14.67 ± 1.36 −12.93 ± 1.76 −10.96 ± 1.63  
p value 0.01 0.02 0.01 0.01 0.01  
  1. Δct value of miR-126, miR-30a and let-7b in ischemic stroke groups and healthy adult. SD stands for the standard deviation of the average Δct of the group. Corresponding p values were calculated using the Independent-samples T test. HA Δct ± SD stands for Δct ± SD of healthy adult.