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Table 2 Prevalence of Seizure, unadjusted and adjusted Prevalence Risk Ratios (PRR) for breakthrough seizures

From: The frequency and precipitating factors for breakthrough seizures among patients with epilepsy in Uganda

  Number with seizure n/N Percentage with seizure (%) Unadjusted PRR 95% CI p-value Adjusted PRR**, 95% CI p-value
Sex
Female 82/111 73.9 0.96 (0.83,1.11)   0.96 (0.84,1.11)  
Male 111/145 76.6 1.0 0.618 1.0 0.581
Age group
18-20 78/97 80.4 1.0   1.0  
21-29 59/80 73.8 0.92 (0.78, 1.08) 0.301 0.91 (0.76,1.08) 0.266
30-44 39/56 69.6 0.87 (0.71,1.06) 0.157 0.86 (0.68, 1.08) 0.181
45+ 17/23 73.9 0.92 (0.71,1.19) 0.529 0.92 (0.65,1.30) 0.633
Marital status
Never married/single 148/195 75.9 1.0   1.0  
Married 35/45 77.8 1.02 (0.86,1.22) 0.784 1.06 (0.85,1.31) 0.602
Divorced/separated/widowed 10/16 62.5 0.82 (0.56, 1.21) 0.327 0.87 (0.56,1.34) 0.531
Level of education
None 13/17 76.5 1.0   1.0  
Primary (P1-P7) 77/101 76.2 1.0 (0.75,1.38) 0.983 0.98 (0.73,1.30) 0.864
Secondary (S1-S6) 77/102 75.5 0.99 (0.74,1.31) 0.930 0.97 (0.73,1.30) 0.842
Tertiary 26/36 72.2 0.94 (0.68, 1.32) 0.737 0.98 (0.70,1.37) 0.897
Duration on Treatment
<1 years 30/32 93.8 1.0   1.0  
1-5 109/150 72.7 0.78 (0.68,0.89) <0.000 0.79 (0.68, 0.91) 0.001
5+ 54/74 73.0 0.78 (0.66,0.92) 0.004 0.82 (0.68,0.98) 0.025
Number of drugs taken
One drug 64/83 77.1 1.0   1.0  
Two drugs 94/124 75.8 0.98 (0.84,1.15) 0.828 0.98 (0.85,1.15) 0.839
Three drugs 35/49 71.4 0.93 (0.75,1.15) 0.481 0.93 (0.76,1.15) 0.525
Doses missed
None 136/187 72.7 1.0   1.0  
1-3 doses 23/32 71.9 0.99 (0.78,1.25) 0.921 1.04 (0.82,1.30) 0.764
> 3 doses 34/37 91.9 1.26 (1.11,1.44) <0.0001 1.33 (1.16,1.52) <0.000
Hours slept (hours)
<=6 18/26 69.2 1.0   1.0  
7-9 109/145 75.2 1.09 (0.83,1.43) 0.555 1.11(0.83,1.49) 0.467
10+ 66/85 77.7 1.12 (0.85,1.49) 0.424 1.18 (0.87,1.59) 0.283
  1. **Adjusted for age, sex, marital status, education level, drug type, duration of anti-epileptic therapy, number of drug doses missed and hours slept at night.
  2. N- total number of study participants, n – number of subjects with seizures.