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Table 4 HRs and 95% CIs for the association between alcohol use disorders and Parkinson’s disease distributed by age of first admission with Parkinson’s disease in the Swedish National Inpatient Register 1972-2008, n = 602,930

From: Alcohol use disorders and risk of Parkinson’s disease: findings from a Swedish national cohort study 1972–2008

  Total population   ≤44   45-59   60-74   ≥75
  n n HRa (95% CI) p-value b n HRa (95% CI) p-value b n HRa (95% CI) p-value b n HRa (95% CI) p-value b
Appendicitis ref 326,403 10 1    53 1    226 1    369 1   
Alcohol model 1c 276,527 14 2.71 (1.20–6.10) 0.016 119 3.58 (2.59–4.94) 0.0001 559 3.78 (3.24–4.41) <.0001 391 1.67 (1.45–1.93) <.0001
 Model 2    2.41 (0.98–5.90) 0.056   1.94 (1.38–2.72) <.0001   2.00 (1.71–2.34) <.0001   1.03 (0.89–1.18) 0.732
 Model 3    2.69 (1.17–6.12) 0.020   3.37 (2.42–4.69) <.0001   3.55 (3.03–4.16) <.0001   1.60 (1.38–1.85) <.0001
 Model 4    2.39 (0.96–5.93) 0.060   1.84 (1.30–2.60) 0.0006   1.84 (1.58–2.18) <.0001   0.91 (0.78–1.06) 0.226
  1. aAbbreviations: HRs, hazard ratios.
  2. bTested with 95% significant level.
  3. cModel 1 crude.
  4. Model 2 adjusted for age at exposure.
  5. Model 3 adjusted for sex.
  6. Model 4 adjusted for age at exposure and sex.