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Table 4 HRs and 95% CIs for the association between alcohol use disorders and Parkinson’s disease distributed by age of first admission with Parkinson’s disease in the Swedish National Inpatient Register 1972-2008, n = 602,930

From: Alcohol use disorders and risk of Parkinson’s disease: findings from a Swedish national cohort study 1972–2008

 

Total population

  ≤44

  45-59

  60-74

  ≥75

 

n

n

HRa

(95% CI)

p-value b

n

HRa

(95% CI)

p-value b

n

HRa

(95% CI)

p-value b

n

HRa

(95% CI)

p-value b

Appendicitis ref

326,403

10

1

  

53

1

  

226

1

  

369

1

  

Alcohol model 1c

276,527

14

2.71

(1.20–6.10)

0.016

119

3.58

(2.59–4.94)

0.0001

559

3.78

(3.24–4.41)

<.0001

391

1.67

(1.45–1.93)

<.0001

 Model 2

  

2.41

(0.98–5.90)

0.056

 

1.94

(1.38–2.72)

<.0001

 

2.00

(1.71–2.34)

<.0001

 

1.03

(0.89–1.18)

0.732

 Model 3

  

2.69

(1.17–6.12)

0.020

 

3.37

(2.42–4.69)

<.0001

 

3.55

(3.03–4.16)

<.0001

 

1.60

(1.38–1.85)

<.0001

 Model 4

  

2.39

(0.96–5.93)

0.060

 

1.84

(1.30–2.60)

0.0006

 

1.84

(1.58–2.18)

<.0001

 

0.91

(0.78–1.06)

0.226

  1. aAbbreviations: HRs, hazard ratios.
  2. bTested with 95% significant level.
  3. cModel 1 crude.
  4. Model 2 adjusted for age at exposure.
  5. Model 3 adjusted for sex.
  6. Model 4 adjusted for age at exposure and sex.