Total population | ≤44 | 45-59 | 60-74 | ≥75 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | n | HRa | (95% CI) | p-value b | n | HRa | (95% CI) | p-value b | n | HRa | (95% CI) | p-value b | n | HRa | (95% CI) | p-value b | |
Appendicitis ref | 326,403 | 10 | 1 | 53 | 1 | 226 | 1 | 369 | 1 | ||||||||
Alcohol model 1c | 276,527 | 14 | 2.71 | (1.20–6.10) | 0.016 | 119 | 3.58 | (2.59–4.94) | 0.0001 | 559 | 3.78 | (3.24–4.41) | <.0001 | 391 | 1.67 | (1.45–1.93) | <.0001 |
Model 2 | 2.41 | (0.98–5.90) | 0.056 | 1.94 | (1.38–2.72) | <.0001 | 2.00 | (1.71–2.34) | <.0001 | 1.03 | (0.89–1.18) | 0.732 | |||||
Model 3 | 2.69 | (1.17–6.12) | 0.020 | 3.37 | (2.42–4.69) | <.0001 | 3.55 | (3.03–4.16) | <.0001 | 1.60 | (1.38–1.85) | <.0001 | |||||
Model 4 | 2.39 | (0.96–5.93) | 0.060 | 1.84 | (1.30–2.60) | 0.0006 | 1.84 | (1.58–2.18) | <.0001 | 0.91 | (0.78–1.06) | 0.226 |