Figure 1

Electrophoretogram of a patient at risk for HD. Several shadow bands can be seen around the main allele bands, but based on the intensity measurement the main bands can easily be determined. The internal size control (not shown) allows the accurate sizing of CAG repeat numbers. In this figure A, B and C depict a non-affected individual, a reduced penetrant CAG repeat mutation carrier and a fully penetrant CAG repeat mutation carrier. Bands with 90, 159 and 168 bp were detected and belong to 15, 38 and 41 CAG repeat numbers respectively.