Figure 2
From: Cortical GABAergic neurons are more severely impaired by alkalosis than acidosis
Excitatory synaptic function at cortical GABAergic neurons is more vulnerable to alkalosis than acidosis. A~C) Waveforms from top to bottom show the recorded sEPSCs under the conditions of control (A), acidosis (B) and alkalosis (C), respectively. The bottom waveforms from each of them are sEPSCs expanded from asterisk-indicated events. Calibration bars are 12 pA, 500 ms for top traces and 8 ms for the expanded traces. D) shows statistical comparisons in the net changes (Δ) of sEPSC amplitudes versus cumulative changes under the conditions of acidosis versus control (open symbols) and alkalosis versus control (dark symbols, p < 0.01; n = 12). E) shows the statistical comparison in the net changes (Δ) of inter-sEPSC-intervals versus cumulative changes under the conditions of acidosis versus control (open symbols) and alkalosis versus control (dark symbols, p < 0.01; n = 12).