Association study between SNP rs150689919 in the DNA demethylation gene, TET1, and Parkinson’s disease in Chinese Han population

Table 3 Genotype and allele frequencies of rs150689919 in EOPD/LOPD patients and controls

SNP	N	Genotype N (%)			p(df, OR)	Allele N (%)		p(df, OR)
SNP	N	CC	CT	TT	p(df, OR)	C	T	p(df, OR)
EOPD	166	156 (94.0)	9 (5.4)	1 (0.6)	0.176^a (df = 2, OR^*)	321 (96.7)	11 (3.3)	0.296^b (df = 1, OR = 0.669)
Controls	195	176 (92.3)	19 (9.7)	0	0.176^a (df = 2, OR^*)	371 (95.1)	19 (4.9)	0.296^b (df = 1, OR = 0.669)
LOPD	348	318 (91.4)	29 (8.3)	1 (0.3)	0.487^c (df = 2, OR^*)	665 (95.5)	31 (4.5)	0.671^d (df = 1, OR = 0.897)
Controls	334	301 (90.1)	33 (9.9)	0	0.487^c (df = 2, OR^*)	635 (95.6)	33 (4.7)	0.671^d (df = 1, OR = 0.897)

p-Values after correcting by binary logistic regression with age and gender using SPSS17.0.
^a p = 0.423; ^b p = 0.432; ^c p = 0.665; ^d p = 0.668.
EOPD, early onset Parkinson’s disease (age at onset ≤ 50); LOPD, late onset Parkinson’s disease (age at onset > 50).
^*With df = 2, the OR value could not been given by Chi-square test.

ISSN: 1471-2377