Table 1 Demographic and clinical characteristics of HCs, all MS patients, and MS subtypes

Age (y)

37±10

40±9

0.112

32±7

48±11

37±9

43±7

0.001^a

mean (±SD)

M/F

18/20

49/97

0.115

6/10

6/13

13/40

17/41

0.001^b

EDSS

4

2.3

5.5

3.0

5.0

0.001^a

median (range)

(1.5-7.0)

(1.5-3.5)

(3.5-7.0)

(2.0-5.0)

(2.5-7.0)

MSSS

5.3

6.3

5.3

5.4

4.9

0.122

median (range)

(1.2-9.5)

(2.1-8.6)

(3.7-9.1)

(1.5-8.6)

(1.6-9.4)

Disease duration (y)

11

1

13

7

16

0.001^a

median (range)

(0–35)

(0–11)

(4–24)

(1–29)

(3–35)

Onset age (y)

28.0

29.3

35.0

27.6

27.0

0.036^c

median (range)

(13.0-57.0)

(18.5-41.0)

(18–57)

(15–46)

(13–44)