Table 1 Demographic, clinical and cognitive features of patients with single lacunar infarction (LI) and patients with associated multiple silent LIs
Variables | Lacunar stroke patients | Odds ratio (95% CI) | Pvalue | t * | |
|---|---|---|---|---|---|
Single LI | Multiple silent | ||||
(n = 34) | LIs (n = 38) | ||||
Age, years, mean (SD) | 73.1 (11.3) | 77.3 (7.7) | 0.999 | -1.834 | |
Women, no. (%) | 17 (50) | 19 (50) | 0.999 | 0.000 | |
Education, mean (SD)† | 8.9 (3.7) | 8.4 (2.9) | 0.71 | 0.672 | |
MMSE, score, mean (SD) | 27.8 (2.3) | 28 (2.0) | 0.686 | -0.406 | |
High BP >140/90 mm Hg, no. (%) | 23 (67.6) | 29 (76.3) | 1.541 (0.546–4.347) | 0.414 | -0.812 |
Diabetes mellitus, no. (%) | 10 (29.4) | 13 (34.2) | 1.248 (0.461–3.381) | 0.663 | -0.430 |
Dyslipidemia, no, (%) | 10 (29.4) | 12 (31.5%) | 1.108 (0.405–3.029) | 0.842 | -0.170 |
Toxic habits, no. (%)‡ | 14 (41.2%) | 15 (39.5%) | 1.073 (0.418–2.756) | 0.883 | -0.372 |
Lacunar syndrome, no. (%) | 0.381 | 0.360 | |||
Pure motor hemiparesis | 9 (26.5) | 10 (26.3) | - | ||
Pure sensory syndrome | 8 (23.5) | 10 (26.3) | 1.125 (0.308–4.104) | ||
Dysarthria–clumsy hand | 5 (14.7) | 9 (23.7) | 1.62 (0.392–6.678) | ||
Sensorimotor syndrome | 4 (11.8) | 1 (2.6) | 0.225 (0.021–2.404) | ||
Ataxic hemiparesis | 2 (5.9) | 0 | |||
Atypical lacunar syndrome | 6 (17.6) | 8 (21.1) | 1.2 (0.298–4.816) | ||
Infarct lateralization, no. (%) | 0.153 | -0.538 | |||
Right | 15 (44.2) | 17 (44.7) | - | ||
Left | 18 (52.9) | 15 (39.5) | 0.735 (0.277–1.950) | ||
Bilateral | 1 (2.9) | 6 (15.8) | 5.294 (0.570–49.136) | ||
Infarct topography, no (%) | 0.014 | -0.883 | |||
Basal ganglia | 2 (5.9) | 6 (15.8) | 7.500 (1.039–54.118) | ||
Corona radiata | 6 (17.6%) | 17 (44.7%) | 7.083 (1.601–31.331) | ||
Internal capsule | 10 (29.4%) | 4 (10.5%) | - | ||
Thalamus | 9 (26.5%) | 9 (23.7) | 2.500 (0.567–11.011) | ||
Pons | 7 (20.6%) | 2 (5.3) | 0.714 (0.101–5.035) | ||
Leukoaraiosis, no. (%) | 17 (50) | 30 (81.1) | 4.286 (1.481–12.4) | 0.007 | -2.886 |