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Table 2 Comparison of clinical characteristics, depression questionnaire results and midbrain SERT binding affinity on 123 I-ADAM between groups of patients with symptoms of depression (BDI and EST-Q score > 11 points) and without symptoms of depression

From: 123I-ADAM SPET imaging of serotonin transporter in patients with epilepsy and comorbid depression

 

Symptoms of depression (n=7)

No symptoms of depression (n=5)

P-value

Age

37.7 (± 10.5)

34.2 (±6.5)

NS

Age at onset

12.4 (±8.4)

18.8 (±8.6)

NS

Duration of epilepsy

25.3 (±10.8)

15.4 (±2.5)

NS

BDI

15.3 (±3.8)

6.0 (±1.4)

0.004

EST-Q

15.8 (±2.6)

7.0 (±1.0)

0.04

123I-ADAM binding to SERT

1.26 (±0.2)

1.216 (±0.2)

NS

  1. NS – not significant; BDI – Beck Depression Inventory; EST-Q - Emotional State Questionnaire; 123I-ADAM – 2-((2-((dimethylamino)methyl)phenyl)thio)-5-(123)iodophenylamine; SERT – serotonin transporter.