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Table 3 Multivariate analysis of prognostic factors

From: Clinical course and seizure outcome of idiopathic childhood epilepsy: determinants of early and long-term prognosis

Prognostic factors   p-value OR 95% CI
Early response to treatment – occurrence of seizures in the initial 12 months
Associated with an increased chance of seizure occurrence
Multiple seizure types   0,000 3,905 1,897-8,035
Status epilepticus 0,051 3,769 0,997-14,249
Associated with a decreased chance of seizure occurrence
Age at seizure onset   0,003 0,707 0,561-0,889
Outcome at 2 years of follow-up – remission of seizures
Associated with an increased chance of remission
Epileptic syndrome (CAE)   0,009 3,174 1,329-7,579
Early response to treatment 0,000 3,291 1,795-6,034
Outcome at 4 years of follow-up – occurrence of seizures in the preceding two years
Associated with an increased chance of seizure occurrence
History of febrile seizures   0,011 2,788 1,271-6,116
History of migraine 0,002 3,446 1,571-7,559
Associated with a decreased chance of seizure occurrence
Academic performance   0,056 0,651 0,419-1,010
Final outcome at the end of follow-up – occurrence of seizures in the preceding two years
Associated with an increased chance of seizure occurrence
History of migraine   0,014 5,305 1,393-20,193
Multiple seizure types 0,069 3,413 0,911-12,789
Initial non response to treatment 0,004 10,95 2,18-54,99
Clinical course – relapsing pattern C
Associated with an increased chance of pattern C-“relapsing” clinical course
Multiple seizure types   0,004 3,308 1,449-7,547
History of migraine 0,03 2,309 1,083-4,922
Associated with a decreased chance of pattern C -“relapsing” clinical course
Early response to treatment   0,013 0,395 0,191-0,820
Age at seizure onset 0,004 0,671 0,511-0,879
  1. OR (odds ratio).
  2. CAE (childhood absence epilepsy).