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Table 2 Clinical characterisation and MRI follow-up of NMO patients with longitudinally extensive transverse myelitis (LETM) (n = 23)

From: Modifications of longitudinally extensive transverse myelitis and brainstem lesions in the course of neuromyelitis optica (NMO): a population-based, descriptive study

Clinical manifestations F/M   Anti-AQP4 antibodies positive F/M   Anti-AQP4 antibodies negative
Number of patients = 17   Number of patients = 6
Duration of disease EDSS Score   Duration of disease EDSS Score
  2-4 y 5-10 y 2-4 5-7 8-9   2-4 y 5-10 y 2-4 5-7 8-9
MRI of the spinal cord
Single LETM 14/3 17 10 7 5 5 7 3/3 6 3 3 1 4 1
Brainstem involvement 7/0 7 5 2 0 1 6 1/0 1 0 1 0 0 1
Relapsing LETM 4/0 4 3 1 0 1 3 1/0 1 1 0 0 1 0
Multiple shorter TM 5/1 6 4 2 0 1 5 1/2 3 2 1 0 2 1
Normal SC 2/1 3 3 0 3 0 0 0 0 0 0 0 0 0
Focal atrophy of SC 0 0 0 0 0 0 0 3/2 5 5 0 0 5 0
General atrophy of SC 4/1 5 4 1 0 0 5 1/1 2 1 1 0 0 2
  1. F/M = Female/male, EDSS = Expanded Disability Status Scale, LETM = longitudinally extensive transverse myelitis, SC = Spinal cord, TM = Transverse myelitis.