Figure 1
From: LINGO1 rs9652490 and rs11856808 polymorphisms are not associated with risk for multiple sclerosis
Scheme and linkage analysis of the SNPs analyzed in this study. The linkage figure was composed with Haploview Ver. 3, release R-2, excluding individuals with > 50% missing genotypes, according to the standard colour scheme (D’/LOD), and the D’ values (×100) are shown when relevant. Top: The area covers the whole LINGO1 gene as well as the 3’ flanking region. The SNPs tested are marked at the right side of the figure. These data correspond to Caucasian individuals (Utah residents with ancestry from northern and western Europe). Bottom: Linkage figures focusing on the two SNPs tested and six SNPs located within the LINGO1 gene. The populations correspond to: CEU, Utah residents with ancestry from northern and western Europe; ASW, African ancestry in Southwest USA; JPT, Japanese in Tokyo, Japan; CHB, Han Chinese in Beijing, China; MXL, Mexican ancestry in Los Angeles, California; TSI, Tuscany in Italia. (see the website http://www.sanger.ac.uk/resources/downloads/human/hapmap3.html).