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Table 2 Study characteristics of the 183 included articles

From: A systematic review of biomarkers for disease progression in Parkinson’s disease

 

All studies (n=183)

Longitudinal studies (n=20)

Cross-sectional studies (n=163)

P value

 

n

%

n

%

n

%

 

Diagnostic criteria

       

  UKPDS Brain Bank criteria

89

48.6

11

55.0

78

47.9

0.472

  Clinical features

53

29.0

8

40.0

45

27.6

  Calne criteria

16

8.7

1

5.0

15

9.2

  National Institute of Neurological Disorders and Stroke criteria

11

6.0

0

0.0

11

6.7

  Weiner and Lang criteria

9

4.9

0

0.0

9

5.5

  Other

5

2.7

0

0.0

5

3.1

Setting

       

  Outpatient

86

47.0

10

50.0

76

46.6

0.859

  Inpatient

2

1.1

0

0.0

2

1.2

  Not detailed

95

51.9

10

50.0

85

52.2

Inclusion/Exclusion criteria

       

  None

1

0.5

0

0.0

1

0.6

0.213

  Mildly restrictive

22

12.0

1

5.0

21

12.9

  Moderately restrictive

65

35.5

11

55.0

54

33.1

  Severely restrictive

35

19.1

1

5.0

34

20.9

  Not detailed

60

32.8

7

35.0

53

32.5

 
  1. The P value column relates to association between study type (longitudinal and cross-sectional studies) and 1) Diagnostic criteria, 2) Setting, 3) Inclusion/exclusion criteria using Pearson’s chi squared tests.