From: A systematic review of biomarkers for disease progression in Parkinson’s disease
All studies (n=183) | Longitudinal studies (n=20) | Cross-sectional studies (n=163) | P value | ||||
---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||
Diagnostic criteria | |||||||
UKPDS Brain Bank criteria | 89 | 48.6 | 11 | 55.0 | 78 | 47.9 | 0.472 |
Clinical features | 53 | 29.0 | 8 | 40.0 | 45 | 27.6 | |
Calne criteria | 16 | 8.7 | 1 | 5.0 | 15 | 9.2 | |
National Institute of Neurological Disorders and Stroke criteria | 11 | 6.0 | 0 | 0.0 | 11 | 6.7 | |
Weiner and Lang criteria | 9 | 4.9 | 0 | 0.0 | 9 | 5.5 | |
Other | 5 | 2.7 | 0 | 0.0 | 5 | 3.1 | |
Setting | |||||||
Outpatient | 86 | 47.0 | 10 | 50.0 | 76 | 46.6 | 0.859 |
Inpatient | 2 | 1.1 | 0 | 0.0 | 2 | 1.2 | |
Not detailed | 95 | 51.9 | 10 | 50.0 | 85 | 52.2 | |
Inclusion/Exclusion criteria | |||||||
None | 1 | 0.5 | 0 | 0.0 | 1 | 0.6 | 0.213 |
Mildly restrictive | 22 | 12.0 | 1 | 5.0 | 21 | 12.9 | |
Moderately restrictive | 65 | 35.5 | 11 | 55.0 | 54 | 33.1 | |
Severely restrictive | 35 | 19.1 | 1 | 5.0 | 34 | 20.9 | |
Not detailed | 60 | 32.8 | 7 | 35.0 | 53 | 32.5 |