Validation of patient determined disease steps (PDDS) scale scores in persons with multiple sclerosis

BMC Neurology

Table 4 Correlations among scores from the EDSS and PDDS with demographic, ambulatory, functional and cognitive outcomes in 96 patients with multiple sclerosis

Variable category	Measure	EDSS	EDSS 95% CI	PDDS	PDDS 95% CI	P-value
Clinical/Demographic	Disease duration	0.199*	(-0.002) - (0.384)	0.202*	(0.002) - (0.387)	.98
	Age	0.446**	(0.270) - (0.593)	0.280**	(0.084) - (0.455)	.19
	Education	-0.352**	(-0.516) - (-0.163)	-0.274**	(-0.450) - (-0.078)	.56
	Income	-0.267**	(-0.444) - (-0.070)	-0.301**	(-0.473) - (-0.107)	.80
Ambulation	6 MW	-0.805**	(-0.866) - (-0.721)	-0.704**	(-0.793) - (-0.586)	.11
	T25FW	0.727**	(0.616) - (0.809)	0.627**	(0.488) - (0.735)	.20
	TUG	0.781**	(0.688) - (0.849)	0.717**	(0.603) - (0.802)	.32
	Accelerometry	-0.717**	(-0.802) - (-0.603)	-0.740**	(-0.819) - (-0.633)	.74
	MSWS-12	0.729**	(0.619) - (0.811)	0.801**	(0.715) - (0.863)	.23
Function	LL-FDI, BLEF	-0.715**	(-0.801) - (-0.601)	-0.748**	(-0.825)- (-0.644)	.63
	LL-FDI, ALEF	-0.727**	(-0.809) - (-0.616)	-0.739**	(-0.818) - (-0.632)	.86
	LL-FDI, UEF	-0.392**	(-0.549) - (-0.208)	-0.445**	(-0.593) -(-0.268)	.66
Cognition	SDMT	-0.404**	(-0.559) - (-0.221)	-0.409**	(-0.563) - (0.227)	.97
	PASAT	-0.261*	(-0.439) - (-0.064)	-0.244*	(-0.424) - (-0.046)	.90

Note. EDSS = Expanded Disability Status Scale, PDDS = Patient Determined Disease Steps scale, P-value for the statistical significance of the difference between correlation coefficients, 6 MW – Six-minute walk, T25FW – Timed-25 Foot Walk, TUG – Timed Up and Go, MSWS-12 – Multiple Sclerosis Walking Scale, LL-FDI – Late-Life Function and Disability Instrument, BLEF – Basic Lower Extremity Function, ALEF – Advanced Lower Extremity Function, UEF – Upper Extremity Function, SDMT – Symbol Digit Modalities Test, and PASAT – Paced Auditory Serial Addition Test, * = p < .05, ** = p < .01.

ISSN: 1471-2377