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Table 1 Demographic and clinical characteristics of Fabry patients at baseline

From: Impaired small fiber conduction in patients with Fabry disease: a neurophysiological case–control study

 

Baseline

FD patients (N)

76

M, F (N)

31, 45

Median age (range)

43 (16–73) years

Patients on ERT N (%)

 

   - M

24/31 (77%)

   - F

10/45 (22%)

Median duration of ERT (range)

4.7 (range 0.1-9.3) years

Patients with GFR ≥60 or <60ml/min/1.73 m2 N (%)

 

   - M ≥60

20/31 (65%)

   - M <60

11/31 (35%)

   - F ≥60

41/45 (91%)

   - F <60

4/45 (9%)

Findings in neurological examination N (%)

 

   - normal

44/76 (58%)

   - hypoesthesia (thermal or tactile)

17/76 (22%)

   - central pattern (e.g. hemiparesis, Babinski sign, brisk reflexes)

8/76 (11%)

   - loss of ankle reflex

4/76 (5%)

   - hypo- or anacusis

4/76 (5%)

   - tactile hyperesthesia

2/76 (3%)

  1. Abbreviations: ERT enzyme replacement therapy, F female, FD Fabry disease, GFR glomerular filtration rate, M male, N number.