TY - JOUR AU - Wijntjes, Juerd AU - Wouda, Ernest J. AU - Siegert, Carl EH AU - Karas, Giorgos B. AU - Vlaar, Annemarie MM PY - 2013 DA - 2013/05/24 TI - Need for prolonged immunosupressive therapy in CLIPPERS-a case report JO - BMC Neurology SP - 49 VL - 13 IS - 1 AB - Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) was first described in 2010 by Pittock and colleagues. All reported patients presented with diplopia and gait ataxia and had similar typical MRI findings with punctuate gadolinium enhancement of the pons. Alternative diagnoses were excluded by means of laboratory, radiological and histological tests. All patients were successfully treated with steroids. We present a case in which the steroid therapy was switched to long term immunosuppressive therapy, leading to several severe side-effects, but sustained clinical improvement. SN - 1471-2377 UR - https://doi.org/10.1186/1471-2377-13-49 DO - 10.1186/1471-2377-13-49 ID - Wijntjes2013 ER -