Table 3 The neuropathologically investigated group - diagnoses and individual levels of CSF markers
From: Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia
Case | Aβ42 (ng/L) | Tau (ng/L) | P-tau (ng/L) | NFL (ng/L) | Clinical diagnosis | Neuropathological diagnosis | Degeneration severity | Dementia duration at LP (years) | Age at death (years) | Brain weight (g) |
|---|---|---|---|---|---|---|---|---|---|---|
1 | 726 | 819 | NA | 5546 | FTD | FTD-TDP43 | moderate | 2 | 54 | 1020 |
2 | 570 | 410 | 35 | 3770 | FTD-MND | FTD-TDP43 | mild | 0.4 | 62 | 1600 |
3 | 420 | 620 | NA | 2600 | bvFTD | FTD-FUS | severe | 3 | 37 | NK |
4 | 500 | 450 | 54 | 1620 | bvFTD | FTD-TDP43 | severe | NK | 67 | 1340 |
5 | 662 | 494 | NA | 1494 | bvFTD | FTD-FUS | severe | 3 | 34 | NK |
6 | 411 | 263 | NA | 1241 | FTD(PPA) | FTD-TDP43 | severe | 12 | 76 | 975 |
7 | 370 | 330 | 29 | 1050 | FTD(PPA) | FTD-TDP43 | severe | 5 | 69 | 760 |
8 | 780 | 490 | 68 | 1030 | bvFTD | FTD-tau | mild | 4 | 81 | 1125 |
9 | 369 | 554 | 95 | 665 | FTD(PPA) | FTD-tau | severe | 7 | 73 | 1010 |
10 | 639 | 528 | NA | <250 | AD | FTD-tau | mild | NK | 53 | 1335 |