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Table 3 The neuropathologically investigated group - diagnoses and individual levels of CSF markers

From: Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia

Case Aβ42 (ng/L) Tau (ng/L) P-tau (ng/L) NFL (ng/L) Clinical diagnosis Neuropathological diagnosis Degeneration severity Dementia duration at LP (years) Age at death (years) Brain weight (g)
1 726 819 NA 5546 FTD FTD-TDP43 moderate 2 54 1020
2 570 410 35 3770 FTD-MND FTD-TDP43 mild 0.4 62 1600
3 420 620 NA 2600 bvFTD FTD-FUS severe 3 37 NK
4 500 450 54 1620 bvFTD FTD-TDP43 severe NK 67 1340
5 662 494 NA 1494 bvFTD FTD-FUS severe 3 34 NK
6 411 263 NA 1241 FTD(PPA) FTD-TDP43 severe 12 76 975
7 370 330 29 1050 FTD(PPA) FTD-TDP43 severe 5 69 760
8 780 490 68 1030 bvFTD FTD-tau mild 4 81 1125
9 369 554 95 665 FTD(PPA) FTD-tau severe 7 73 1010
10 639 528 NA <250 AD FTD-tau mild NK 53 1335
  1. PPA Primary progressive aphasia.
  2. NA Not analysed.
  3. NK Not known.