Table 4 Results from log-linear models (binomial function), OR and 95%CI

First author and reference

Lorraine 1990-2002

1

1

1

1

1

Debouverie 2007 [31]

Reggio Emilia 85-1989

0.33

0.37

0.25

0.28

0.18

Guidetti 1995 [36]

(0.24-0.45)

(0.29-0.48)

(0.17-0.36)

(0.19-0.42)

(0.09-0.37)

UK cohort 1993-2000

1.22

0.57

1.66

1.59

1.55

Alonso 2007 [48]

(0.94-1.59)

(0.48-0.66)

(1.30-2.13)

(1.28-1.96)

(1.03-2.35)

Catania 1990-1999

0.98

0.90

0.87

0.84

0.90

Nicoletti 2005 [32]

(0.72-1.32)

(0.72-1.12)

(0.63-1.20)

(0.61-1.17)

0.53-1.50)

Faroe Islands 86-2007

0.94

0.83

0.91

0.80

1.02

Joensen 2011 [19]

(0.63-1.39)

(0.55-1.25)

(0.57-1.48)

(0.45-1.45)

(0.49-2.10)

Västerbotten 88-1997

1.07

1.03

1.00

0.96

1.02

Sundström 2003 [37]

(0.79-1.46)

(0.81-1.32)

(0.72-1.39)

(0.68-1.36)

(0.61-1.70)

Ferrara 90-2003

0.74

0.79

0.64

0.74

0.49

Granieri 2007 [34]

(0.55-0.99)

(0.65-0.97)

(0.48-0.86)

(0.55-0.98)

(0.29-0.81)

San Marino 90-2005

1.44

1.43

1.19

1.34

0.81

Granieri 2008 [35]

(0.93-2.23)

(0.92-2.23)

(0.66-2.15)

(0.71-2.54)

(0.25-2.61)

Catania 2000-2004

1.39

1.19

1.43

1.06

2.07

Nicoletti 2011 [10]

(1.01-1.91)

(0.90-1.57)

(1.01-2.00)

(0.72-1.57)

(1.26-3.38)

West Indies 1992-2007

0.21

0.19

0.21

0.26

0.11

Cabre 2009 [8]

(0.16-0.29)

(0.15-0.25)

(0.15-0.29)

(0.19-0.35)

(0.06-0.22)

Age-groups

0-14y

0.01

0.01

-

-

-

(0.008-0.02)

(0.008-0.02)

15-24y

0.50

0.47

-

-

-

(0.39-0.64)

(0.42-0.52)

25-34y

1

1

-

-

-

35-44y

0.84

-

1

1

1

(0.67-1.04)

45-54y

0.56

-

0.66

0.61

0.71

(0.44-0.71)

(0.55-0.78)

(0.52-0.71)

(0.52-0.97)

55-64y

0.19

-

0.21

0.17

0.29

(0.14-0.25)

(0.17-0.27)

(0.14-0.22)

(0.20-0.44)

≥65y

0.02

-

0.02

0.02

0.03

(0.01-0.04)

(0.01-0.04)

(0.01-0.04)

(0.01-0.06)

Sex (reference men)

2.19

2.81

1.96

-

-

(1.87-2.57)

(2.51-3.14)

(1.67-2.31)

Mid time point incidence period *

1.09

1.06

1.12

1.07

1.20

(1.04-1.15)

(1.01-1.12)

(1.05-1.20)

(0.99-1.15)

(1.07-1.34)

Latitude degrees*

1.04

1.03

1.05

1.04

1.06

(1.03-1.05)

(1.02-1.04)

(1.03-1.06)

(1.02-1.05)

(1.03-1.08)

Diagnostic criteria*

Poser

1

1

1

1

1

Other than Poser’s (McAlpine) MRI data not considered

0.73

0.71

0.77

0.59

0.99

(0.41-1.30)

(0.40-1.26)

(0.35-1.67)

(0.25-1.41)

(0.25-3.87)

McDonald or Poser and MacDonald including MRI evidence of spread

0.68

0.43

0.94

1.06

0.76

(0.55-0.85)

(0.35-0.53)

(0.71-1.22)

(0.80-1.41)

(0.49-1.26)