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Table 6 Measures of validity of UTHSR data against “gold standard” based on 115 patient records, 2008–2011

From: The University of Texas Houston Stroke Registry (UTHSR): implementation of enhanced data quality assurance procedures improves data quality

Categorical variables Dichotomous variables UTHSR vs. “gold standard”
F* N Agreement (%) Sensitivity (%) (95% CI) Specificity (%) (95% CI)
Gender Male 43 85 100 100 (92.0, 100) 100 (92.0, 100)
Stroke type Infarct 62 115 100 100 (94.2, 100) 100 (93.3, 100)
ICH 31 115 100 100 (88.8, 100) 100 (95.7, 100)
TIA 2 115 100 100 (15.8, 100) 100 (96.8, 100)
Hospital arrival mode Air 35 115 97.4 97.2 (85.5, 99.9) 97.5 (91.2, 99.7)
Ambulance 59 115 97.4 95.2 (86.5, 99.0) 100 (93.3, 100)
tPA therapy Yes 25 115 100 100 (86.3, 100) 100 (96.0, 100)
tPA location MHH-TMC 13 25 100 100 (75.3, 100) 100 (73.5, 100)
IA therapy No 13 115 98.3 99.0 (94.6, 99.9) 92.9 (66.1, 99.8)
Atrial fibrillation in hospital Yes 19 115 99.1 99.0 (94.6, 99.9) 99.0 (94.3, 99.9)
Anti-thrombotic medication Yes 52 78 100 100 (82.4, 100) 100 (86.8, 100)
DVT prophylaxis Yes 78 85 100 100 (95.4, 100) 100 (59.0, 100)
Patient education Yes 63 78 100 100 (94.3, 100) 100 (78.2, 100)
Wake up stroke Yes 11 78 98.7 91.7 (61.5, 99.8) 100 (94.6, 100)
Rehabilitation evaluation Yes 67 78 100 100 (94.6, 100) 100 (72.0, 100)
Symptomatic hemorrhage Yes 2 115 100 100 (15.8, 100) 100 (96.8, 100)
Disposition at discharge Death 17 115 100 100 (80.5, 100) 100 (96.3, 100)
Home 43 115 98.3 100 (91.8, 100) 97.2 (90.3, 99.7)
Inpatient rehabilitation 18 115 100 100 (81.5, 100) 100 (96.3, 100)
Skilled nursing facility 4 111 96.5 NR 100 (99.9, 100)
Initial presentation MHH 76 115 99.1 100 (95.3, 100) 97.4 (86.5, 99.9)
Smoker Yes 20 78 100 100 (83.2, 100) 100 (94.0, 100)
Continuous variables   N Agreement (%) Correlation (95% CI) MD(95% CI)
Age (years)   115 98.3 0.96 (0.94, 0.97) 0.5 (−0.3, 1.2)
Onset time (minutes)   72 97.2 1.00 (1.00, 1.00) 6.3 (−3.0, 15.5)
Arrival time (minutes)   115 85.2 1.00 (1.00, 1.00) 26.7 (−36.3, 89.6)
tPA time (minutes)   23 95.7 1.00 (1.00, 1.00) −0.04 (−0.13, 0.05)
CT Time (minutes)   52 80.8 1.00 (1.00, 1.00) 20.9 (−19.7, 61.4)
Glucose   78 96.2 0.86 (0.79, 0.91) −5.9 (−15.6, 3.8)
Creatinine   78 98.7 0.99 (0.99, 1.00) 0.003 (−0.003, 0.008)
LDL   86 97.7 0.96 (0.94, 0.98) 114.9 (−113.5, 343.3)
INR   104 94.2 0.99 (0.99, 1.00) −0.003 (−0.013, 0.006)
mRS on discharge   104 98.1 0.99 (0.99, 1.00) 0 (−0.03, 0.03)
  1. N = Where both UTHSR and gold standard data have values; 95% CI = 95% Confidence Interval; ✝ MD = Mean Difference, (calculated as UTHSR minus the “gold standard”).
  2. NR = Not reported because there were no observations in UTHSR in the category of “Skilled Nursing Facility”; * F = Frequency of observations for each level of dichotomous variable reported.