Total white blood cell count or neutrophil count predict ischemic stroke events among adult Taiwanese: report from a community-based cohort study

Table 2 Median WBC count, number of study participants, incidence case, person-years, rate, and HRs by WBC quintile for the association with ischemic stroke in the participants

	Quintile of baseline white blood cell count
	Q1	Q2	Q3	Q4	Q5	P for trend	P for Hosmer and Lemeshow test
Median WBC count, per μl	4400	5400	6100	7000	8500
Individuals, n	715	715	672	673	641
Incident cases, n	31	35	32	42	47
person-years	10232	10094	9548	9568	8731
Rate(/1000 person-year)	3	3.5	3.4	4.4	5.4
HR, model 1*^,†	1	1.21 (0.74-1.96)	1.17 (0.71-1.91)	1.62 (1.02-2.58)	2.00 (1.27-3.15)	0.0008	0.72
HR, model 2*^,‡	1	1.25 (0.76-2.03)	1.19 (0.72-1.97)	1.65 (1.03-2.64)	2.06 (1.30-3.27)	0.0006	0.33
HR, model 3*^,§	1	1.18 (0.72-1.95)	1.00 (0.59-1.67)	1.34 (0.82-2.19)	1.67 (1.02-2.73)	0.03	0.23

*Data for HR (95% CI) are expressed relative to WBC count quintile1.
^†Model 1: Adjusted for age and sex.
^‡Model 2: Model 1 plus BMI, alcohol intake, smoking, marital status, education level, occupation, exercise, family history of diabetes and hypertension.
^§Model 3: Model 2 plus systolic blood pressure, diastolic blood pressure, diabetes, total cholesterol, triglyceride, low density lipoprotein, high density lipoprotein, atrial fibrillation, left ventricular hypertrophy, and coronary artery disease.

ISSN: 1471-2377