Quintile of baseline neutrophil count | |||||||
---|---|---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | Q5 | P for trend | P for Hosmer and Lemeshow test | |
Median neutrophil count, per μl | 2500 | 3300 | 3800 | 4500 | 5900 | ||
Individuals, n | 694 | 615 | 603 | 631 | 610 | ||
Incident cases, n | 24 | 35 | 28 | 37 | 44 | ||
person-years | 10113 | 8756 | 8476 | 8939 | 8238 | ||
Rate(/1000 person-year) | 2.4 | 4 | 3.3 | 4.1 | 5.3 | ||
HR, model 1*,† | 1 | 1.59 (0.95-2.68) | 1.41 (0.82-2.43) | 1.66 (0.99-2.79) | 2.27 (1.38-3.76) | 0.002 | 0.79 |
HR, model 2*,‡ | 1 | 1.63 (0.96-2.77) | 1.47 (0.85-2.56) | 1.72 (1.02-2.91) | 2.32 (1.39-3.87) | 0.002 | 0.25 |
HR, model 3*,§ | 1 | 1.52 (0.88-2.61) | 1.22 (0.69-2.17) | 1.52 (0.89-2.62) | 1.93 (1.13-3.29) | 0.02 | 0.45 |