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Table 1 The characteristics and the frequencies of jugular venous reflux and plasma endothelin-1 levels in cough syncope/pre-syncope patients and control subjects

From: Jugular venous reflux and plasma endothelin-1 are associated with cough syncope: a case control pilot study

 

Cough syncope/pre-syncope (n = 17)

Controls (n = 51)

p value

Age, mean (SD), yr

74.63 (12.37)

74.63 (12.37)

 

Gender, M/F

15/2

45/6

 

Vascular risk factors, n (%)

   

HTN

4 (23.53%)

10 (19.61%)

0.729

Diabetes mellitus

1 (5.88%)

5 (9.80%)

0.365

Hyperlipidemia

0

4 (7.84%)

0.307

Smoking

13 (76.47%)

41 (80.39%)

0.729

COPD

14 (82.35%)

34 (66.67%)

0.219

GOLD I

6 (43%)

15 (44%)

GOLD II

6 (43%)

12 (35%)

GOLD III

2 (14%)

7 (21%)

Right-side JVR, n (%)

13 (76.47%)

25 (49.02%)

0.048

Left-side JVR, n (%)

11 (64.71%)

18 (35.29%)

0.034

Both-side JVR, n (%)

10 (58.82%)

8 (15.69%)

0.0005

Plasma ET-1 level, pg/ml

3.64 (1.23)

2.39 (1.01)

<0.0001

  1. Abbreviations: HTN = hypertension; COPD = chronic obstructive pulmonary disease; GOLD = Global Initiative for Chronic Obstructive Lung Disease guideline; JVR = jugular venous reflux; ET-1 = endothelin-1; SAH, subarachnoid hemorrhage.