|
Parameter
|
Patients (n = 67)
|
Controls (n = 21)
|
p
|
|---|
|
Female/male (%)
|
48.0/52.0
|
33.3/66.7
|
ns*
|
|
Age (years ± SD)
|
35.7 ± 9.5
|
32.9 ± 10.1
|
ns‡
|
|
Age at onset (years ± SD)
|
27.6 ± 7.5
|
-
| |
|
Disease course, n (%)
| |
-
| |
|
CIS
|
5 (7.5)
|
|
RR
|
41 (61.2)
|
|
CP
|
21 (31.3)
|
|
Disease duration (years ± SD)
|
9.1 ± 6.3
|
-
| |
|
EDSS (mean ± SD)
|
3.9 ± 2.1
|
-
| |
|
3.8§
|
|
MSSS (mean ± SD)
|
5.4 ± 2.7
|
-
|
0.000002#,$
|
|
in RR group
|
4.6 ± 2.0
| | |
|
in CP group
|
7.4 ± 1.3
| | |
- CIS: clinically isolated syndrome; RR: relapsing-remitting; CP: chronic progressive (including secondary progressive and primary progressive); EDSS: Expanded Disability Status Scale; MSSS: Multiple Sclerosis Severity Score; * χ
2 ; § median; ‡ ANOVA; # ANOVA for RR vs. CP patients; $ Scheffe’s post-hoc test for RR vs. CP patients; the values represent the means ± S.D.
