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Table 2 Total scores of impairment on neuropsychological tests

From: Cognitive and neuropsychiatric impairment in cerebral radionecrosis patients after radiotherapy of nasopharyngeal carcinoma

Variable No-RT RT-No-CRN RT + CRN * pValue pValue
  (n = 36) (n = 40) (n = 40)   
MMSE 28.9 ± 1.9 28.6 ± 1.5 25.4 ± 4.6 <0.001 <0.001
Time to complete MMSE (min) 4.0 ± 1.1 5.9 ± 1.7 5.7 ± 1.4 <0.001 0.886
MoCA 27.2 ± 2.2 27.2 ± 3.0 21.8 ± 5.3 <0.001 <0.001
Time to complete MoCA (min) 6.4 ± 1.2 8.3 ± 2.3 8.1 ± 2.0 <0.001 1.000
ADL 20.0 ± 0 20.0 ± 0 23.7 ± 9.5 0.012 0.001
NPI 3.5 ± 6.7 3.5 ± 4.5 15.6 ± 17.0 <0.001 <0.001
HAMD 4.9 ± 4.1 2.9 ± 3.0 9.7 ± 6.3 <0.001 <0.001
HAMA 5.5 ± 4.1 3.8 ± 2.8 10.7 ± 7.8 <0.001 <0.001
  1. Data are presented as mean ± SD.
  2. *Comparison between the RT + CRN group and No-RT group.
  3. Comparison between the RT + CRN group and the RT-No-CRN group.