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Table 2 Total scores of impairment on neuropsychological tests

From: Cognitive and neuropsychiatric impairment in cerebral radionecrosis patients after radiotherapy of nasopharyngeal carcinoma

Variable

No-RT

RT-No-CRN

RT + CRN

* pValue

pValue

 

(n = 36)

(n = 40)

(n = 40)

  

MMSE

28.9 ± 1.9

28.6 ± 1.5

25.4 ± 4.6

<0.001

<0.001

Time to complete MMSE (min)

4.0 ± 1.1

5.9 ± 1.7

5.7 ± 1.4

<0.001

0.886

MoCA

27.2 ± 2.2

27.2 ± 3.0

21.8 ± 5.3

<0.001

<0.001

Time to complete MoCA (min)

6.4 ± 1.2

8.3 ± 2.3

8.1 ± 2.0

<0.001

1.000

ADL

20.0 ± 0

20.0 ± 0

23.7 ± 9.5

0.012

0.001

NPI

3.5 ± 6.7

3.5 ± 4.5

15.6 ± 17.0

<0.001

<0.001

HAMD

4.9 ± 4.1

2.9 ± 3.0

9.7 ± 6.3

<0.001

<0.001

HAMA

5.5 ± 4.1

3.8 ± 2.8

10.7 ± 7.8

<0.001

<0.001

  1. Data are presented as mean ± SD.
  2. *Comparison between the RT + CRN group and No-RT group.
  3. Comparison between the RT + CRN group and the RT-No-CRN group.