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Table 4 Frequency of impairment on NPI (overall and individual symptoms) in 3 groups

From: Cognitive and neuropsychiatric impairment in cerebral radionecrosis patients after radiotherapy of nasopharyngeal carcinoma

Variable

No-RT

RT-No-CRN

RT + CRN

* pValue

pValue

pValue

 

(n = 36)

(n = 40)

(n = 40)

   

Presence of symptoms in past 4 weeks, n (%)

      

Any symptom

18(50.0)

24(60.0)

33(82.5)

0.354

<0.001

0.006

Delusions

0(0)

0(0)

2(5.0)

-

0.209

0.209

Hallucinations

0(0)

0(0)

2(5.0)

-

0.209

0.209

Depression/dysphoria

9(25.0)

7(17.5)

25(62.5)

0.407

0.002

<0.001

Anxiety

15(41.7)

15(37.5)

29(72.5)

0.815

0.007

0.001

Agitation/aggression

1(2.8)

3(7.5)

12(30.0)

0.620

0.003

0.009

Elation

0(0)

0(0)

3(8.6)

-

0.093

0.093

Disinhibition

0(0)

0(0)

2(5.0)

-

0.209

0.209

Irritability/liability

6(16.7)

22(55.0)

35(87.5)

0.002

<0.001

0.001

Apathy/indifference

4(11.1)

4(10.0)

12(30.0)

1.000

0.053

0.023

Aberrant motor activity

0(0)

0(0)

3(8.6)

-

0.093

0.093

Night-time behavior disturbances

2(5.6)

0(0)

6(15.0)

0.209

0.259

0.007

Appetite/eating abnormalities

0(0)

0(0)

3(8.6)

-

0.093

0.093

  1. *Comparison between the No-RT group and RT-No-CRN group.
  2. Comparison between the No-RT group and RT + CRN group.
  3. Comparison between the RT-No-CRN group and RT + CRN group.