Skip to main content

Table 4 Frequency of impairment on NPI (overall and individual symptoms) in 3 groups

From: Cognitive and neuropsychiatric impairment in cerebral radionecrosis patients after radiotherapy of nasopharyngeal carcinoma

Variable No-RT RT-No-CRN RT + CRN * pValue pValue pValue
  (n = 36) (n = 40) (n = 40)    
Presence of symptoms in past 4 weeks, n (%)       
Any symptom 18(50.0) 24(60.0) 33(82.5) 0.354 <0.001 0.006
Delusions 0(0) 0(0) 2(5.0) - 0.209 0.209
Hallucinations 0(0) 0(0) 2(5.0) - 0.209 0.209
Depression/dysphoria 9(25.0) 7(17.5) 25(62.5) 0.407 0.002 <0.001
Anxiety 15(41.7) 15(37.5) 29(72.5) 0.815 0.007 0.001
Agitation/aggression 1(2.8) 3(7.5) 12(30.0) 0.620 0.003 0.009
Elation 0(0) 0(0) 3(8.6) - 0.093 0.093
Disinhibition 0(0) 0(0) 2(5.0) - 0.209 0.209
Irritability/liability 6(16.7) 22(55.0) 35(87.5) 0.002 <0.001 0.001
Apathy/indifference 4(11.1) 4(10.0) 12(30.0) 1.000 0.053 0.023
Aberrant motor activity 0(0) 0(0) 3(8.6) - 0.093 0.093
Night-time behavior disturbances 2(5.6) 0(0) 6(15.0) 0.209 0.259 0.007
Appetite/eating abnormalities 0(0) 0(0) 3(8.6) - 0.093 0.093
  1. *Comparison between the No-RT group and RT-No-CRN group.
  2. Comparison between the No-RT group and RT + CRN group.
  3. Comparison between the RT-No-CRN group and RT + CRN group.