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Table 3 Normalised subcortical structure volumes and FA and MD values in focal neocortical epilepsy patients

From: Evaluation of subcortical grey matter abnormalities in patients with MRI-negative cortical epilepsy determined through structural and tensor magnetic resonance imaging

Subcortical structures

Volume (×10-3)

FA

MD (×10-3)

 

Controls

Patients

p

t

Controls

Patients

p

t

Controls

Patients

p

t

Hipp L

3.011 (0.440)

2.797 (0.547)

0.119

2.052

0.183 (0.019)

0.171 (0.026)

0.052

0.038

1.030 (0.053)

1.074 (0.105)

0.051

-1.870

Caud L

3.143 (0.506)

2.848 (0.469)

0.034*

0.430

0.279 (0.042)

0.275 (0.042)

0.738

-0.336

0.846 (0.069)

0.853 (0.052)

0.669

-2.184

Puta L

4.362 (0.521)

4.128 (0.301)

0.057

1.300

0.194 (0.023)

0.194 (0.024)

0.995

0.006

0.780 (0.031)

0.791 (0.032)

0.200

-1.945

Pall L

1.432 (0.259)

1.438 (0.363)

0.945

1.346

0.353 (0.055)

0.371 (0.069)

0.282

1.086

0.790 (0.036)

0.804 (0.042)

0.184

0.069

Accu L

0.383 (0.116)

0.374 (0.068)

0.723

2.000

0.295 (0.049)

0.265 (0.055)

0.038*

-1.991

0.840 (0.049)

0.832 (0.040)

0.512

-1.585

Thal L

6.300 (0.761)

5.969 (0.454)

0.067

1.608

0.291 (0.026)

0.291 (0.023)

0.970

-0.788

0.863 (0.059)

0.894 (0.050)

0.045*

-2.188

Amyg L

0.868 (0.214)

0.749 (0.176)

0.033*

-0.661

0.197 (0.020)

0.193 (0.018)

0.435

-2.132

0.858 (0.039)

0.877 (0.047)

0.114

-0.357

Hipp R

3.314 (0.427)

3.159 (0.474)

0.216

0.614

0.196 (0.019)

0.188 (0.020)

0.126

1.197

1.042 (0.053)

1.101 (0.102)

0.009*

-1.801

Caud R

3.040 (0.720)

3.032 (0.402)

0.960

1.097

0.260 (0.038)

0.249 (0.038)

0.286

-1.079

0.886 (0.076)

0.913 (0.103)

0.278

-0.051

Puta R

4.297 (0.548)

4.002 (0.334)

0.025*

1.836

0.214 (0.026)

0.206 (0.027)

0.245

-1.176

0.776 (0.034)

0.792 (0.032)

0.072

-2.305

Pall R

1.486 (0.258)

1.428 (0.285)

0.441

2.163

0.403 (0.056)

0.397 (0.058)

0.689

-0.403

0.771 (0.041)

0.979 (0.046)

0.035*

-0.777

Accu R

0.297 (0.109)

0.268 (0.076)

0.275

2.702

0.285 (0.053)

0.240 (0.047)

0.002*

-1.555

0.842 (0.048)

0.847 (0.056)

0.726

-1.253

Thal R

6.086 (0.767)

5.751 (0.538)

0.078

-0.569

0.272 (0.028)

0.281 (0.028)

0.237

-1.715

0.881 (0.062)

0.893 (0.076)

0.542

-1.028

Amyg R

0.788 (0.223)

0.723 (0.237)

0.309

0.353

0.205 (0.020)

0.196 (0.017)

0.092

-3.218

0.869 (0.047)

0.862 (0.043)

0.572

-1.102

  1. Hipp = hippocampus; Caud = caudate nucleus; Puta = putamen; Pall = globus pallidus; Accu = nucleus accumbens; Thal = thalamus; Amyg = amygdala; R = right hemisphere; L = left hemisphere; *denotes a significant difference xp < 0.05) with respect to controls.