Skip to main content

Advertisement

Table 2 Descriptive statistics and treatment effects at 1 year follow-up

From: One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with multiple sclerosis

Primary outcome measures Baseline (n = 159) Follow-up 1 (n = 146) Follow-up 2 (n = 144) Follow-up 3 (n = 131)
Global fatigue severity (GFS) subscale of the FAI (potential range 1 to 7, high scores indicate more fatigue)
FACETS mean (SD) 5.60 (0.98) 5.48 (0.92) 5.26 (1.03) 5.32 (1.00)
CLP mean (SD) 5.61 (1.09) 5.55 (1.17) 5.66 (0.93) 5.70 (1.01)
Mean difference in change from baseline [95% CI] - −0.03 (−0.33 to 0.28) −0.36 (−0.63 to −0.08) −0.30 (−0.61 to 0.01)
p value - 0.86 0.01 0.06
Std effect size - −0.03 −0.35 −0.29
Multiple Sclerosis Impact Scale-29 (MSIS-29) (potential range 0 to 100, high scores indicate more impact)
FACETS mean (SD) 49.6 (19.1) 47.3 (18.2) 44.9 (19.2) 46.2 (19.1)
CLP mean (SD) 43.9 (17.6) 42.2 (18.4) 43.0 (17.3) 47.2 (17.4)
Mean difference in change from baseline [95% CI] - 1.44 (−2.36 to 5.24) −1.56 (−6.45 to 3.34) −4.34 (−8.61 to −0.08)
p value - 0.46 0.53 0.046
Std effect size - 0.08 −0.08 −0.24
MS Fatigue Self-Efficacy scale (MS-FSE) (potential range 10 to 100, high scores indicate more certainty in controlling fatigue
FACETS mean (SD) 45 (17) 57 (17) 56 (19) 56 (16)
CLP mean (SD) 49 (16) 50 (17) 53 (17) 52 (17)
Mean difference in change from baseline [95% CI] - 9 (4 to 14) 6 (0 to 12) 6 (−1 to 12)
p value - 0.001 0.048 0.09
Std effect size - 0.54 0.36 0.34
Statistically significant secondary outcome measures
Vitality subscale of the SF-36 (potential range 0 to 100, high scores indicate higher quality of life)
FACETS mean (SD) 32.0 (16.8) 35.6 (19.4) 37.4 (20.3) 37.70 (18.75)
CLP mean (SD) 35.1 (19.7) 33.4 (16.8) 34.4 (17.30 32.43 (17.69)
Mean difference in change from baseline [95% CI] - 4.42 (−1.22 to 10.06) 6.38 (0.45 to 12.32) 6.64 (0.84 to 12.44)
p value - 0.12 0.04 0.03
Std effect size - 0.24 0.35 0.37
Multiple Sclerosis Impact Scale-29 (MSIS-29) - Physical subscale (potential range 0 to100, high scores indicate more impact)
FACETS mean (SD) 51.4 (21.4) 48.8 (19.7) 47.0 (21.3) 47.4 (21.0)
CLP mean (SD) 46.6 (20.3) 44.9 (20.5) 46.5 (19.8) 50.5 (20.1)
Mean difference in change from baseline [95% CI] - 1.39 (−2.87 to 5.65) −0.81 (−5.91 to 4.28) −4.74 (−9.40 to −0.08)
p value - 0.52 0.75 0.046
Std effect size - 0.07 −0.04 −0.23