Table 1 Demographics, utility, MS-specific QOL, IPA scores and economic costs in entire survey sample and 3 groups separated by EDSS values

No

41

17

17

7

Age (year)

42.8 (9.5)*

37.9 (9.7) §

45.5 (5.4) §

48.3 (12.2)

Sex-ratio M/W

7/34

3/14

2/15

2/5

Education level (year)

12.0 (3.3)

12.1 (3.4)

12.3 (3.4)

10.9 (3.1)

Disease duration (year)

11.7 (7.4)*

8.5 (5.3) §

11.1 (4.8) ¶

20.9 (10) § ¶

EDSS

4.0 (1.6)*

2.5 (0.8) §

4.7 (0.6) §

6.2 (0.4) §

No of currently employed patients

24

14

10

0

Full time employment (%)

39%

53%

15%

0%

EQ5D-VAS score

0.52 (0.28)*

0.65 (0.31) §

0.44 (0.23) §

0.42 (0.24)

MSQOL-P

51.1 (19.1)

59.5 (21.4)

44.1 (17.0)

47.9 (10.1)

MSQOL-M

55.1 (24)

60.2 (23.2)

51.8 (23.8)

45.0 (14.3)

IPA

Autonomy indoors

0.91 (0.82)*

0.54 (0.57) §

1.17 (0.83) §

1.34 (1.14)

Family role

1.7 (0.8)*

1.21 (0.67) §

2.14 (0.68) §

1.91 (0.75)

Autonomy outdoors

1.89 (1.08)*

1.19 (0.88) § ¶

2.49 (0.89) §

2.36 (0.96) ¶

Social life

1.1 (0.65)*

0.87 (0.69) §

1.14 (0.54)

1.71 (0.5) §

Work and education

2.54 (1.32)*

1.74 (1.18) §

3.22 (1.0) §

3.12 (1.28)

Costs (€):

Total cost

68448 (33374)*

52505 (26570) §

70337 (31975)

102581 (26963) §

Direct medical cost

34210 (3818)*

33062 (3793) §

34571 (3972)

36123 (2893) §

Direct non medical cost

10521 (8297)*

5525 (4651) § ¶

11885 (7289) ¶

19290 (9686) §

Informal care

2902 (2689)*

1594 (1637) §

3271 (2285)

5181 (3981) §

Indirect cost

23725 (25871)

13918 (20907) §

23879 (27042)

47167 (20799) §